Page last updated: 2024-10-06

superpathway of megalomicin A biosynthesis

Proteins (8)

ProteinSynonymsTaxonomy
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminaseEC 2.6.1.106
TDP-4-keto-6-deoxyglucose 2,3 dehydratase
TDP-4-keto-6-deoxyhexose 3,5-epimerase
TDP-megosamine glycosyltransferase
TDP-4-keto-6-deoxyhexose 4-ketoreductase
Daunosaminyl-N,N-dimethyltransferase
TDP-4-keto-6-deoxyhexose 2,3-reductase
TDP-4-keto-6-deoxyglucose-2,3-dehydratase

Compounds (21)

CompoundDescription
diphosphoric acid
hydronium ion
Ammonium
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
thymidine 5'-triphosphateRN given refers to parent cpd
6-deoxyerythronolide bStreptomyces erythreus metabolite; presumed intermediate in biosynthesis of erythromycins; structure given in first source
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
alpha-Ketoglutarate
5'-deoxyadenosinemain heading DEOXYADENOSINE refers to the 3' cpd
glutamate
glucose-1-phosphateRN given refers to (alpha-D-Glc)-isomer
thymidine 5'-diphosphatesee also record for thymidine 3',5'-diphosphate, RN 2863-04-9
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Coenzyme A
dTDP-4-amino-4,6-dideoxy-glucosestructure in first source
deoxythymidine diphosphate-glucosestructure given in first source
erythronolide bintermediate of erythromycin biogenesis; structure in first source
propionyl-coenzyme ARN given refers to parent cpd