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superpathway of histidine, purine, and pyrimidine biosynthesis

Proteins (0)

Compounds (51)

CompoundDescription
phosphoric acidconcise etchant is 37% H3PO4
guanosine monophosphateA guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature.
ammonium hydroxideThe hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
NADH
fumaratesCompounds based on fumaric acid.
Adenosine TriphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
glutamineA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
uridine monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
Uridine TriphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
phosphoribosyl pyrophosphateThe key substance in the biosynthesis of histidine, tryptophan, and purine and pyrimidine nucleotides.
glycineA non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
hydrogen carbonate
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
2'-deoxyguanosine 5'-phosphateRN given refers to parent cpd.
deoxyguanosine triphosphate
guanosine diphosphateA guanine nucleotide containing two phosphate groups esterified to the sugar moiety.
guanosine triphosphateGuanosine 5'-(tetrahydrogen triphosphate). A guanine nucleotide containing three phosphate groups esterified to the sugar moiety.
inosinic acid
5,6,7,8-tetrahydrofolic acidRN given refers to (DL)-isomer
adenylosuccinate
phosphoribosyl-N-formylglycineamide
glycineamide ribonucleotidestructure
phosphoribosyladenosine triphosphate
ribose-1,5-bisphosphateRN given for (D)-isomer
2'-deoxyadenosine triphosphateRN given refers to unlabeled parent cpd
alpha-Ketoglutarate
2'-deoxyadenosine triphosphateRN given refers to unlabeled parent cpd
n(1)-((5'-phosphoribulosyl)formimino)-5-aminoimidazo-4-carboxamide ribonucleotidestructure given in first source; an intermediate in imidazole glycerol phosphate synthesis
carbamyl phosphateThe monoanhydride of carbamic acid with PHOSPHORIC ACID. It is an important intermediate metabolite and is synthesized enzymatically by CARBAMYL-PHOSPHATE SYNTHASE (AMMONIA) and CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING).
formic acidRN given refers to parent cpd
ribose 1-phosphateRN given refers to (D)-isomer
glutamate
HydrogenThe first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
NADA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
cytidine diphosphateCytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate.
histidineAn essential amino acid that is required for the production of HISTAMINE.
Cytidine TriphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
xanthosine 5'-triphosphateRN given refers to parent cpd
histidinalan intermediate in the conversion of L-histidinol to L-istidine by histidinol dehydrogenase; RN given refers to (S)-isomer
orotidylic acidstructure
saicaradenosylsuccinase catalyzes its conversion to AICAR
aminoimidazole ribotide
histidinolThe penultimate step in the pathway of histidine biosynthesis. Oxidation of the alcohol group on the side chain gives the acid group forming histidine. Histidinol has also been used as an inhibitor of protein synthesis.
carboxyaminoimidazole ribotidereacts with alanosine to form antimetabolite; substrate for EC 4.1.1.21; structure in second source
5-formamidoimidazole-4-carboxamide ribotidepurine precursor
aica ribonucleotidepurine precursor that has antineoplastic activity
ureidosuccinic acid, (L)-isomer