Page last updated: 2024-10-06

superpathway of heme biosynthesis

Proteins (8)

ProteinSynonymsTaxonomy
Uroporphyrinogen-III synthaseUROIIIS; UROS; EC 4.2.1.75; Hydroxymethylbilane hydrolyase [cyclizing]; Uroporphyrinogen-III cosynthaseSaccharomyces cerevisiae S288C
Protoporphyrinogen oxidasePPO; EC 1.3.3.4Saccharomyces cerevisiae S288C
Delta-aminolevulinic acid dehydrataseALADH; EC 4.2.1.24; Porphobilinogen synthaseSaccharomyces cerevisiae S288C
Porphobilinogen deaminasePBG; EC 2.5.1.61; Hydroxymethylbilane synthase; HMBS; Pre-uroporphyrinogen synthaseSaccharomyces cerevisiae S288C
5-aminolevulinate synthase, mitochondrialEC 2.3.1.37; 5-aminolevulinic acid synthase; Delta-ALA synthase; Delta-aminolevulinate synthaseSaccharomyces cerevisiae S288C
Oxygen-dependent coproporphyrinogen-III oxidaseCOX; Coprogen oxidase; Coproporphyrinogenase; EC 1.3.3.3Saccharomyces cerevisiae S288C
Uroporphyrinogen decarboxylaseUPD; URO-D; EC 4.1.1.37Saccharomyces cerevisiae S288C
Ferrochelatase, mitochondrialEC 4.99.1.1; Heme synthase; Protoheme ferro-lyaseSaccharomyces cerevisiae S288C

Compounds (15)

CompoundDescription
hydronium ion
Ammonium
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
succinyl-coenzyme A
preuroporphyrinogen
Porphobilinogen
protoporphyrinogen
coproporphyrinogen III
Coenzyme A
EthacridineA topically applied anti-infective agent.
hemeThe color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.