Page last updated: 2024-10-06

superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)

Proteins (20)

ProteinSynonymsTaxonomy
Farnesyl pyrophosphate synthase 1, mitochondrialFPP synthase 1; FPS 1; EC 2.5.1.10; (2E,6E)-farnesyl diphosphate synthase 1; Dimethylallyltranstransferase 1; 2.5.1.1; Farnesyl diphosphate synthase 1; Geranyltranstransferase 1Arabidopsis thaliana (thale cress)
Farnesyl pyrophosphate synthase 2FPP synthase 2; FPS 2; EC 2.5.1.10; (2E,6E)-farnesyl diphosphate synthase 2; Dimethylallyltranstransferase 2; 2.5.1.1; Farnesyl diphosphate synthase 2; Geranyltranstransferase 2Arabidopsis thaliana (thale cress)
Solanesyl diphosphate synthase 3, chloroplastic/mitochondrial EC 2.5.1.85; All-trans-nonaprenyl-diphosphate synthase 3 (geranylgeranyl-diphosphate specific); Geranyl diphosphate synthase 1; Trans-type polyprenyl pyrophosphate synthase; AtPPPSArabidopsis thaliana (thale cress)
Solanesyl diphosphate synthase 2, chloroplasticAtSPS2; EC 2.5.1.85; All-trans-nonaprenyl-diphosphate synthase 2 (geranylgeranyl-diphosphate specific)Arabidopsis thaliana (thale cress)
Solanesyl diphosphate synthase 1, chloroplasticAtSPS1; EC 2.5.1.85; All-trans-nonaprenyl-diphosphate synthase 1 (geranylgeranyl-diphosphate specific); Geranylgeranyl diphosphate synthase; 2.5.1.29Arabidopsis thaliana (thale cress)
Hydroxymethylglutaryl-CoA synthaseHMG-CoA synthase; EC 2.3.3.10; 3-hydroxy-3-methylglutaryl coenzyme A synthase; Protein EMBRYO DEFECTIVE 2778; Protein FLAKY POLLEN 1Arabidopsis thaliana (thale cress)
Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 1, chloroplasticGGPP synthase 1; GGPS1; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 1; Dimethylallyltranstransferase 1; 2.5.1.1; Farnesyl diphosphate synthase 1; Farnesyltranstransferase 1; 2.5.1.29; Geranyltranstransferase 1; 2.5.1.10Arabidopsis thaliana (thale cress)
Isopentenyl-diphosphate Delta-isomerase I, chloroplasticEC 5.3.3.2; Isopentenyl pyrophosphate isomerase I; IPP isomerase IArabidopsis thaliana (thale cress)
Isopentenyl-diphosphate Delta-isomerase II, chloroplasticEC 5.3.3.2; Isopentenyl pyrophosphate isomerase II; IPP isomerase IIArabidopsis thaliana (thale cress)
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1AtHMGR1; HMG-CoA reductase 1; EC 1.1.1.34Arabidopsis thaliana (thale cress)
Acetyl-CoA acetyltransferase, cytosolic 1EC 2.3.1.9; Cytosolic acetoacetyl-CoA thiolase 1; Thiolase 1; Protein EMBRYO DEFECTIVE 1276Arabidopsis thaliana (thale cress)
Probable acetyl-CoA acetyltransferase, cytosolic 2EC 2.3.1.9; Cytosolic acetoacetyl-CoA thiolase 2; Thiolase 2Arabidopsis thaliana (thale cress)
Heterodimeric geranylgeranyl pyrophosphate synthase large subunit 2GGPP synthase 2; GGPS2; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 2; Dimethylallyltranstransferase 2; 2.5.1.1; Farnesyl diphosphate synthase 2; Farnesyltranstransferase 2; 2.5.1.29; Geranyltranstransferase 2; 2.5.1.10Arabidopsis thaliana (thale cress)
Geranylgeranyl pyrophosphate synthase 6, mitochondrial GGPP synthase 6; GGPS6; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 6; Dimethylallyltranstransferase 6; 2.5.1.1; Farnesyl diphosphate synthase 6; Farnesyltranstransferase 6; 2.5.1.29; Geranyltranstransferase 6; 2.5.1.10Arabidopsis thaliana (thale cress)
Diphosphomevalonate decarboxylase MVD1, peroxisomalEC 4.1.1.33; Mevalonate 5-diphosphate decarboxylase 1; AtMDD1; AtMVD1Arabidopsis thaliana (thale cress)
Mevalonate kinaseMK; EC 2.7.1.36Arabidopsis thaliana (thale cress)
Geranylgeranyl pyrophosphate synthase 12, chloroplasticGGPP synthase 12; GGPS12; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 12; Dimethylallyltranstransferase 12; 2.5.1.1; Farnesyl diphosphate synthase 12; Farnesyltranstransferase 12; 2.5.1.29; Geranyltranstransferase 12; 2.5.1.10Arabidopsis thaliana (thale cress)
Geranylgeranyl pyrophosphate synthase 11, chloroplasticGGPP synthase 11; GGPS11; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 11; Dimethylallyltranstransferase 11; 2.5.1.1; Farnesyl diphosphate synthase 11; Farnesyltranstransferase 11; 2.5.1.29; Geranyltranstransferase 11; 2.5.1.10Arabidopsis thaliana (thale cress)
Geranylgeranyl pyrophosphate synthase 3, chloroplastic GGPP synthase 3; GGPS3; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 3; Dimethylallyltranstransferase 3; 2.5.1.1; Farnesyl diphosphate synthase 3; Farnesyltranstransferase 3; 2.5.1.29; Geranyltranstransferase 3; 2.5.1.10Arabidopsis thaliana (thale cress)
Geranylgeranyl pyrophosphate synthase 4GGPP synthase 4; GGPS4; EC 2.5.1.-; (2E,6E)-farnesyl diphosphate synthase 4; Dimethylallyltranstransferase 4; 2.5.1.1; Farnesyl diphosphate synthase 4; Farnesyltranstransferase 4; 2.5.1.29; Geranyltranstransferase 4; 2.5.1.10Arabidopsis thaliana (thale cress)

Compounds (17)

CompoundDescription
diphosphoric acid
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
isopentenyl pyrophosphatesubstrate for isopentenyl pyrophosphate isomerase; RN given refers to unlabeled cpd; a nonpeptide mycobacterial antigen that stimulates gamma delta T cells
farnesyl pyrophosphatea sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation
geranyl diphosphatestructure in first source
Mevalonate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
geranylgeranyl pyrophosphateRN given refers to (E,E,E)-isomer
Coenzyme A
acetoacetyl CoA
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.