| Protein | Synonyms | Taxonomy |
|---|
| Tryprostatin B synthase | EC 2.5.1.106; Brevianamide F prenyltransferase; Fumitremorgin biosynthesis protein B | Aspergillus fumigatus Af293 |
| Nonribosomal peptide synthetase 13 | EC 6.3.3.-; Brevianamide F synthase; Fumitremorgin biosynthesis protein A | Aspergillus fumigatus |
| Verruculogen prenyltransferase | EC 2.5.1.107 | Aspergillus fischeri NRRL 181 |
| Tryprostatin B 6-hydroxylase | EC 1.14.14.118; Fumitremorgin biosynthesis protein C | Aspergillus fumigatus |
| 6-hydroxytryprostatin B O-methyltransferase | EC 2.1.1.293; Fumitremorgin biosynthesis protein D | Aspergillus fumigatus |
| Fumitremorgin C synthase | EC 1.14.19.71; Fumitremorgin biosynthesis protein E | Aspergillus fumigatus |
| 12-alpha,13-alpha-dihydroxyfumitremorgin C prenyltransferase | EC 2.5.1.110; Fumitremorgin biosynthesis protein H | Aspergillus fumigatus |
| Verruculogen synthase | EC 1.14.11.38; Fumitremorgin biosynthesis protein F | Aspergillus fumigatus Af293 |
| Fumitremorgin C monooxygenase | EC 1.14.14.119; Fumitremorgin biosynthesis protein G | Aspergillus fumigatus |
| Compound | Description |
|---|
| diphosphoric acid | |
| hydronium ion | |
| Succinate | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| demethoxyfumitremorgin c | isolated from the fermentation broth of Aspergillus fumigatus; a mammalian cell cycle inhibitor; structure given in first source |
| fumitremorgin b | intermediary in TR-2 mycotoxin biosyn; RN given refers to (5aR-(5aalpha,6alpha,12beta,14aalpha))-isomer; structure given in first source |
| fumitremorgin a | isolated from fungus Aspergillus fumigatus; structure given in first source; RN given refers to (5R-(5alpha,10alpha,10aalpha,14aalpha,15balpha))-isomer |
| verruculogen | complex 6-O-methylindole cpd containing 3 nitrogens; induces tremor; tremorigenic metabolite from Penicillium verruculosum isolated from moldy peanuts; decreases GABA levels in CNS; structure |
| alpha-Ketoglutarate | |
| brevianamide f | isolated from the endophyte from Aspergillus fumigatus associated with Melia azedarach L that could be used to develop a natural eco-friendly herbicide.structure in first source |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| tryprostatin b | isolated from Aspergillus fumigatus; a mammalian cell cycle inhibitor; structure given in first source |
| tryprostatin a | isolated from Aspergillus fumigatus; a mammalian cell cycle inhibitor; structure given in first source |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| tryptoquivaline | tremor-producing metabolite from Aspergillus clavatus; tetrapeptide derived from tryptophan, anthranilic acid, valine, & methylalanine; structure & N1 names previously assigned to tryptoquivaline C & tryptoquivaline D found to be incorrect & are revised in third source; see also record for tryptoquivalone; structure in third source |