| Protein | Synonyms | Taxonomy |
|---|
| Porphobilinogen deaminase | PBG-D; EC 2.5.1.61; Hydroxymethylbilane synthase; HMBS; Pre-uroporphyrinogen synthase | Homo sapiens (human) |
| 5-aminolevulinate synthase, erythroid-specific, mitochondrial | ALAS-E; EC 2.3.1.37; 5-aminolevulinic acid synthase 2; Delta-ALA synthase 2; Delta-aminolevulinate synthase 2 | Homo sapiens (human) |
| Ferrochelatase, mitochondrial | EC 4.99.1.1; Heme synthase; Protoheme ferro-lyase | Homo sapiens (human) |
| Uroporphyrinogen decarboxylase | UPD; URO-D; EC 4.1.1.37 | Homo sapiens (human) |
| Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial | COX; Coprogen oxidase; Coproporphyrinogenase; EC 1.3.3.3 | Homo sapiens (human) |
| Delta-aminolevulinic acid dehydratase | ALADH; EC 4.2.1.24; Porphobilinogen synthase | Homo sapiens (human) |
| Protoporphyrinogen oxidase | PPO; EC 1.3.3.4 | Homo sapiens (human) |
| Uroporphyrinogen-III synthase | UROIIIS; UROS; EC 4.2.1.75; Hydroxymethylbilane hydrolyase [cyclizing]; Uroporphyrinogen-III cosynthase | Homo sapiens (human) |
| 5-aminolevulinate synthase, nonspecific, mitochondrial | ALAS-H; EC 2.3.1.37; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1 | Homo sapiens (human) |
| 5-aminolevulinate synthase 2 | EC 2.3.1.37; 5-aminolevulinic acid synthase; Delta-ALA synthase; Delta-aminolevulinate synthase | Cereibacter sphaeroides 2.4.1 |
| Compound | Description |
|---|
| hydronium ion | |
| pyridoxal | The 4-carboxyaldehyde form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. |
| Rubidium | An element that is an alkali metal. It has an atomic symbol Rb, atomic number 37, and atomic weight 85.47. It is used as a chemical reagent and in the manufacture of photoelectric cells. |
| Ammonium | |
| copper sulfate | A sulfate salt of copper. It is a potent emetic and is used as an antidote for poisoning by phosphorus. It also can be used to prevent the growth of algae. |
| Mercury | A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing. |
| Copper | A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Manganese | A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035) |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Lithium | An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| iodine | A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically. |
| potassium | An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| uroporphyrin III | |
| succinyl-coenzyme A | |
| preuroporphyrinogen | |
| iodoacetamide | An alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate. |
| phenylglyoxal | A reagent that is highly selective for the modification of arginyl residues. It is used to selectively inhibit various enzymes and acts as an energy transfer inhibitor in photophosphorylation. |
| diethyl pyrocarbonate | Preservative for wines, soft drinks, and fruit juices and a gentle esterifying agent. |
| ethylmaleimide | A sulfhydryl reagent that is widely used in experimental biochemical studies. |
| diacetyl | Carrier of aroma of butter, vinegar, coffee, and other foods. |
| Porphobilinogen | |
| hydrogen cyanide | Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials. |
| coproporphyrin I | RN given refers to cpd with specified locants; see also record for coproporphyrin III; zinc coproporphyrin I is fluorescent and a characteristic component of meconium |
| coproporphyrin III | RN given refers to unlabeled parent cpd; see also record for coproporphyrin I |
| protoporphyrinogen | |
| coproporphyrinogen III | |
| Coenzyme A | |
| Ethacridine | A topically applied anti-infective agent. |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |
| heme | The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. |
| Haematoporphyrin IX | |