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superpathway of aromatic compound degradation

Proteins (33)

ProteinSynonymsTaxonomy
3-dehydroquinate dehydratase3-dehydroquinase; EC 4.2.1.10; Type II DHQaseCorynebacterium glutamicum ATCC 13032
Quinate/shikimate dehydrogenase (NAD(+))QSDH; EC 1.1.1.-; EC 1.1.1.24Corynebacterium glutamicum ATCC 13032
Protocatechuate 3,4-dioxygenase beta subunit Corynebacterium glutamicum ATCC 13032
NAD-dependent aldehyde dehydrogenases Corynebacterium glutamicum ATCC 13032
Protocatechuate 3,4-dioxygenase beta subunit Corynebacterium glutamicum ATCC 13032
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Corynebacterium glutamicum ATCC 13032
Adenylosuccinate lyase Corynebacterium glutamicum ATCC 13032
Adenylosuccinate lyase Corynebacterium glutamicum ATCC 13032
Gentisate 1,2-dioxygenaseCorynebacterium glutamicum ATCC 13032
2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase Corynebacterium glutamicum ATCC 13032
2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductasesCorynebacterium glutamicum ATCC 13032
Muconolactone Delta-isomerase Corynebacterium glutamicum ATCC 13032
Protocatechuate 3,4-dioxygenase beta subunit Corynebacterium glutamicum ATCC 13032
Acetyl-CoA acetyltransferasesCorynebacterium glutamicum ATCC 13032
Acyl-CoA:acetate CoA transferase beta subunit Corynebacterium glutamicum ATCC 13032
Flavodoxin reductases Corynebacterium glutamicum ATCC 13032
Alcohol dehydrogenase IV Corynebacterium glutamicum ATCC 13032
MDMPI_N domain-containing proteinCorynebacterium glutamicum ATCC 13032
Uncharacterized ACR, homolog of gamma-carboxymuconolactone decarboxylase subunitCorynebacterium glutamicum ATCC 13032
Uncharacterized ACR, homolog of gamma-carboxymuconolactone decarboxylase subunit Corynebacterium glutamicum ATCC 13032
Predicted hydrolases or acyltransferases Corynebacterium glutamicum ATCC 13032
Acyl-CoA:acetate CoA transferase alpha subunit Corynebacterium glutamicum ATCC 13032
Uncharacterized ACR, homolog of gamma-carboxymuconolactone decarboxylase subunit Corynebacterium glutamicum ATCC 13032
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Corynebacterium glutamicum ATCC 13032
Uncharacterized proteinCorynebacterium glutamicum ATCC 13032
Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenasesCorynebacterium glutamicum ATCC 13032
3-dehydroshikimate dehydratase Corynebacterium glutamicum ATCC 13032
Dehydrogenases with different specificities Corynebacterium glutamicum ATCC 13032
Protocatechuate 3,4-dioxygenase beta subunit Corynebacterium glutamicum ATCC 13032
O-succinylbenzoate synthase and related enzymes Corynebacterium glutamicum ATCC 13032
Alcohol dehydrogenase IV Corynebacterium glutamicum ATCC 13032
Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenasesCorynebacterium glutamicum ATCC 13032
Protocatechuate 3,4-dioxygenase beta subunit Corynebacterium glutamicum ATCC 13032

Compounds (38)

CompoundDescription
hydronium ion
CobaltA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
vanillinon-line & Index Medicus search FLAVORING AGENTS (82-83); RN given refers to parent cpd; structure
Succinate
NADH
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
resorcinolRN given refers to parent cpd; structure in Merck Index, 9th ed, #7951
fumaratesCompounds based on fumaric acid.
formaldehydeA highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
NickelA trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
phenolAn antiseptic and disinfectant aromatic alcohol.
succinyl-coenzyme A
2,5-dihydroxybenzoic acidRN given refers to parent cpd; a oxidative product of saligenin
Vanillic AcidA flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).
nedocromilA pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including EOSINOPHILS; NEUTROPHILS; MACROPHAGES; MAST CELLS; MONOCYTES; AND PLATELETS.
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
hydroxyhydroquinone
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Benzoate
catecholRN given refers to unlabeled parent cpd
mycothiola glyco-inositol-cysteine found in MYCOBACTERIUM BOVIS which conjugates exogenous compounds for detoxication; it is a microbe counterpart to eucaryotic GLUTATHIONE; acted on by mycothiol disulfide reductase and mycothiol S-conjugate amidase and MDF dehydrogenase;
TolbutamideA sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)
3-dehydroshikimate
Quinate
muconolactoneRN given refers to unlabeled parent cpd; structure given in first source
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)