| Protein | Synonyms | Taxonomy |
|---|
| Salicylate hydroxylase | EC 1.14.13.1; Salicylate 1-monooxygenase | Pseudomonas putida |
| Mandelate racemase | MR; EC 5.1.2.2 | Pseudomonas putida |
| p-hydroxybenzoate hydroxylase | PHBH; PHBHase; EC 1.14.13.2; 4-hydroxybenzoate 3-monooxygenase | Pseudomonas fluorescens |
| Metapyrocatechase | MPC; EC 1.13.11.2; CatO2ase; Catechol 2,3-dioxygenase | Pseudomonas putida |
| Protocatechuate 2,3-dioxygenase | | Paenibacillus sp. JJ-1b |
| Benzoylformate decarboxylase | BFD; BFDC; EC 4.1.1.7 | Pseudomonas putida |
| 3-dehydroshikimate dehydratase | 3-DHS dehydratase; DHSase; EC 4.2.1.118 | Acinetobacter baylyi ADP1 |
| Catabolic 3-dehydroquinate dehydratase | 3-dehydroquinase; EC 4.2.1.10 | Acinetobacter baylyi ADP1 |
| Kynureninase | EC 3.7.1.3; L-kynurenine hydrolase | Pseudomonas fluorescens |
| 4-hydroxy-2-oxovalerate aldolase 1 | HOA 1; EC 4.1.3.39; 4-hydroxy-2-keto-pentanoic acid aldolase 1; 4-hydroxy-2-oxopentanoate aldolase 1 | Pseudomonas putida F1 |
| 4-hydroxy-2-oxovalerate aldolase | HOA; EC 4.1.3.39; 4-hydroxy-2-keto-pentanoic acid aldolase; 4-hydroxy-2-oxopentanoate aldolase | Pseudomonas putida |
| Naphthalene 1,2-dioxygenase system, large oxygenase component | EC 1.14.12.12; ISP NAP; Naphthalene 1,2-dioxygenase ISP alpha; Naphthalene 1,2-dioxygenase subunit alpha; ND subunit alpha; NDO subunit alpha | Pseudomonas putida |
| 2-hydroxymuconic semialdehyde dehydrogenase | HMSD; EC 1.2.1.85 | Pseudomonas putida |
| 4-oxalocrotonate decarboxylase | | Paenibacillus sp. JJ-1b |
| 4-oxalocrotonate decarboxylase | 4-OD; EC 4.1.1.77 | Pseudomonas putida |
| Salicylaldehyde dehydrogenase | EC 1.2.1.65 | Pseudomonas putida |
| 2-hydroxychromene-2-carboxylate isomerase | HCCA isomerase; EC 5.99.1.4 | Pseudomonas putida |
| 2-hydroxymuconate tautomerase | EC 5.3.2.6; 4-oxalocrotonate tautomerase; 4-OT | Pseudomonas putida |
| 3-methylcatechol 2,3-dioxygenase | EC 1.13.11.- | Pseudomonas putida F1 |
| Cis-toluene dihydrodiol dehydrogenase | EC 1.3.1.- | Pseudomonas putida F1 |
| Anthranilate 1,2-dioxygenase large subunit | EC 1.14.12.1 | Acinetobacter baylyi ADP1 |
| Anthranilate 1,2-dioxygenase small subunit | EC 1.14.12.1 | Acinetobacter baylyi ADP1 |
| Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | EC 1.18.1.3 | Pseudomonas putida F1 |
| 2-hydroxy-6-oxo-2,4-heptadienoate hydrolase | HOHH; EC 3.7.1.25 | Pseudomonas putida F1 |
| Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase | THBPA hydratase-aldolase; EC 4.1.2.45; 2'-hydroxybenzalpyruvate aldolase | Pseudomonas putida |
| 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase | EC 1.3.1.25; 2-hydro-1,2-dihydroxybenzoate dehydrogenase; DHB dehydrogenase; Cis-1,2-dihydroxy-3,4-cyclohexadiene-1-carboxylate dehydrogenase; Cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase | Pseudomonas putida |
| Anthranilate 1,2-dioxygenase electron transfer component | | Acinetobacter baylyi ADP1 |
| Toluate 1,2-dioxygenase subunit alpha | EC 1.14.12.- | Pseudomonas putida |
| Toluate 1,2-dioxygenase subunit beta | EC 1.14.12.- | Pseudomonas putida |
| Toluate 1,2-dioxygenase electron transfer component | | Pseudomonas putida |
| 2-hydroxypent-2,4-dienoate hydratase | HPH; EC 4.2.-.-; 2-oxopent-4-enoate hydratase | Pseudomonas putida |
| Benzaldehyde dehydrogenase [NAD(+)] | EC 1.2.1.28 | Pseudomonas putida |
| Naphthalene 1,2-dioxygenase system ferredoxin--NAD(P)(+), reductase component | EC 1.18.1.7; Ferredoxin--NAD(P)(+) reductase (naphthalene dioxygenase ferredoxin-specific) | Pseudomonas putida |
| Quinate/shikimate dehydrogenase (quinone) | EC 1.1.5.8; NAD(P)-independent quinate dehydrogenase | Acinetobacter baylyi ADP1 |
| NAD(P)-dependent benzaldehyde dehydrogenase | EC 1.2.1.28; EC 1.2.1.7 | Pseudomonas putida |
| Acetaldehyde dehydrogenase | | Pseudomonas putida |
| PobA protein | | Pseudomonas putida |
| Salicylate hydroxylase | | Stutzerimonas stutzeri |
| Salicylate 1-hydroxylase | | Pseudomonas reinekei |
| 1,2-dihydroxynaphthalene dioxygenase | | Pseudomonas putida |
| Cis-1, 2-dihydro-1, 2-dihydroxynaphtalene-1, 2-dehydrogenase NahB | | Pseudomonas putida |
| 2-hydroxymuconate-6-semialdehyde dehydrogenase | | Paenibacillus sp. JJ-1b |
| Tautomerase | | Paenibacillus sp. JJ-1b |
| 5-carboxy-2-hydroxymuconate-6-semialdehyde decarboxylase | | Paenibacillus sp. JJ-1b |
| Naphthalene 1,2-dioxygenase system, small oxygenase component | Naphthalene 1,2-dioxygenase ISP beta; Naphthalene 1,2-dioxygenase subunit beta; ND subunit beta; NDO subunit beta | Pseudomonas putida |
| (S)-mandelate dehydrogenase | EC 1.1.99.31; L(+)-mandelate dehydrogenase; MDH | Pseudomonas putida |
| 2-hydroxymuconate semialdehyde hydrolase | HMSH; EC 3.7.1.9; 2-hydroxymuconic semialdehyde hydrolase | Pseudomonas putida |
| 4-nitrobenzaldehyde dehydrogenase NtnC | | |
| Naphthalene 1,2-dioxygenase system, ferredoxin component | | Pseudomonas putida |
| Toluene 1,2-dioxygenase system ferredoxin subunit | | Pseudomonas putida F1 |
| Compound | Description |
|---|
| diphosphoric acid | |
| hydronium ion | |
| Cobalt | A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. |
| Rubidium | An element that is an alkali metal. It has an atomic symbol Rb, atomic number 37, and atomic weight 85.47. It is used as a chemical reagent and in the manufacture of photoelectric cells. |
| toluene | A widely used industrial solvent. |
| oxyquinoline | An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics. |
| NADH | |
| Ammonium | |
| Mercury | A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing. |
| Copper | A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Manganese | A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035) |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| carbon monoxide | Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed) |
| fluorides | Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices. |
| Iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| iodine | A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically. |
| chlorine | An element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family. |
| Orthophosphate | |
| Flavin Mononucleotide | A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues. |
| potassium | An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Nickel | A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| salicylates | The salts or esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis. |
| nedocromil | A pyranoquinolone derivative that inhibits activation of inflammatory cells which are associated with ASTHMA, including EOSINOPHILS; NEUTROPHILS; MACROPHAGES; MAST CELLS; MONOCYTES; AND PLATELETS. |
| 1,2-naphthoquinone | |
| Pyruvic Acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| 1,2-dihydroxynaphthalene | RN given refers to parent cpd |
| 4-hydroxybenzaldehyde | |
| 1,10-phenanthroline | RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases |
| 4-hydroxybenzoic acid | |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| acetaldehyde | A colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis. |
| benzaldehyde | RN given refers to parent cpd; structure |
| Benzoate | |
| formate | |
| catechol | RN given refers to unlabeled parent cpd |
| 4-fluorobenzoate | |
| Nitrilotriacetic Acid | A derivative of acetic acid, N(CH2COOH)3. It is a complexing (sequestering) agent that forms stable complexes with Zn2+. (From Miall's Dictionary of Chemistry, 5th ed.) |
| 3-methylcatechol | |
| ethylmaleimide | A sulfhydryl reagent that is widely used in experimental biochemical studies. |
| 4-aminobenzoic acid | An aminobenzoic acid isomer that combines with pteridine and GLUTAMIC ACID to form FOLIC ACID. The fact that 4-aminobenzoic acid absorbs light throughout the UVB range has also resulted in its use as an ingredient in SUNSCREENS. |
| Edetic Acid | A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive. |
| anthranilate | |
| Tolbutamide | A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290) |
| 3-dehydroshikimate | |
| hydrogen cyanide | Hydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials. |
| 2,2'-dipyridyl | A reagent used for the determination of iron. |
| Quinate | |
| PQQ Cofactor | A pyrrolo-quinoline having two adjacent keto-groups at the 4 and 5 positions and three acidic carboxyl groups. It is a coenzyme of some DEHYDROGENASES. |
| Coenzyme A | |
| Acetyl Coenzyme A | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |
| salicylaldehyde | RN in Chemline for tin chloride: 40958-40-5 |
| naphthalene | structure in Merck Index, 9th ed, #6194 |
| 4-methylcatechol | structure |