| Protein | Synonyms | Taxonomy |
|---|
| Acetylornithine/succinyldiaminopimelate aminotransferase | ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 | Escherichia coli K-12 |
| Carbamoyl-phosphate synthase small chain | EC 6.3.5.5; Carbamoyl-phosphate synthetase glutamine chain | Escherichia coli K-12 |
| Amino-acid acetyltransferase | EC 2.3.1.1; N-acetylglutamate synthase; AGS; NAGS | Escherichia coli K-12 |
| 4-aminobutyrate aminotransferase GabT | EC 2.6.1.19; 5-aminovalerate transaminase; 2.6.1.48; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBAT | Escherichia coli K-12 |
| S-adenosylmethionine decarboxylase proenzyme | AdoMetDC; SAMDC; EC 4.1.1.50 | Escherichia coli K-12 |
| Inducible lysine decarboxylase | LDCI; EC 4.1.1.18 | Escherichia coli K-12 |
| Constitutive lysine decarboxylase | LDCC; EC 4.1.1.18 | Escherichia coli K-12 |
| Agmatinase | EC 3.5.3.11; Agmatine ureohydrolase; AUH | Escherichia coli K-12 |
| Biosynthetic arginine decarboxylase | ADC; EC 4.1.1.19 | Escherichia coli K-12 |
| Acetylglutamate kinase | EC 2.7.2.8; N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; NAGK | Escherichia coli K-12 |
| Acetylornithine deacetylase | AO; Acetylornithinase; EC 3.5.1.16; N-acetylornithinase; NAO | Escherichia coli K-12 |
| Carbamoyl-phosphate synthase large chain | EC 6.3.5.5; Carbamoyl-phosphate synthetase ammonia chain | Escherichia coli K-12 |
| Ornithine carbamoyltransferase subunit I | OTCase-1; EC 2.1.3.3 | Escherichia coli K-12 |
| Ornithine carbamoyltransferase subunit F | OTCase-2; EC 2.1.3.3 | Escherichia coli K-12 |
| Polyamine aminopropyltransferase | Cadaverine aminopropyltransferase; 2.5.1.-; Putrescine aminopropyltransferase; PAPT; Spermidine aminopropyltransferase; 2.5.1.79; Spermidine synthase; SPDS; SPDSY; 2.5.1.16; Spermine synthase; 2.5.1.22; Thermospermine synthase | Escherichia coli K-12 |
| N-acetyl-gamma-glutamyl-phosphate reductase | AGPR; EC 1.2.1.38; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase | Escherichia coli K-12 |
| Argininosuccinate lyase | ASAL; EC 4.3.2.1; Arginosuccinase | Escherichia coli K-12 |
| Constitutive ornithine decarboxylase | EC 4.1.1.17 | Escherichia coli K-12 |
| Compound | Description |
|---|
| diphosphoric acid | |
| hydronium ion | |
| Aluminum | A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98. |
| Cobalt | A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. |
| urea | A compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids. |
| Arginine | An essential amino acid that is physiologically active in the L-form. |
| Ammonium | |
| Mercury | A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing. |
| Copper | A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Manganese | A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035) |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Lithium | An element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER. |
| Iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| Aspartate | |
| fumarates | Compounds based on fumaric acid. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| hydrogen carbonate | |
| potassium | An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Nickel | A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| monofluoromethylagmatine | arginine decarboxylase inhibitor |
| cyanates | Organic salts of cyanic acid containing the -OCN radical. |
| Pyruvic Acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| alpha-Ketoglutarate | |
| Cadmium | An element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING. |
| Carbamyl Phosphate | The monoanhydride of carbamic acid with PHOSPHORIC ACID. It is an important intermediate metabolite and is synthesized enzymatically by CARBAMYL-PHOSPHATE SYNTHASE (AMMONIA) and CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING). |
| Cadaverine | A foul-smelling diamine formed by bacterial decarboxylation of lysine. |
| ethylmaleimide | A sulfhydryl reagent that is widely used in experimental biochemical studies. |
| 5'-methylthioadenosine | structure |
| Edetic Acid | A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive. |
| glutamate | |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| polyglutamine | RN given for (D)-isomer |
| Spermidine | A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine. |
| Uridine Monophosphate | 5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| Coenzyme A | |
| N-(3-aminopropyl)cadaverine | |
| sapropterin | RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases |
| Acetyl Coenzyme A | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| phenylhydrazine | RN given refers to parent cpd |
| dicyclohexylammonium | |
| N(delta)-(phosphonoacetyl)-L-ornithine | |
| 2-amino-4-oxo-5-chloropentanoate | inhibitor of asparagine synthetase; structure |
| ethylglyoxal bis(guanylhydrazone) | RN given refers to parent cpd |
| 2-fluoromethylornithine | an ornithine decarboxylase antagonist |