Page last updated: 2024-10-06

superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis

Proteins (24)

ProteinSynonymsTaxonomy
Bifunctional protein GlmUEscherichia coli K-12
Glucose-6-phosphate isomeraseGPI; EC 5.3.1.9; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHIEscherichia coli K-12
UDP-N-acetyl-D-mannosamine dehydrogenaseEC 1.1.1.336; UDP-ManNAc 6-dehydrogenaseEscherichia coli K-12
Phosphoglucosamine mutaseEC 5.4.2.10Escherichia coli K-12
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]EC 2.6.1.16; D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine--D-fructose-6-phosphate amidotransferaseEscherichia coli K-12
UDP-N-acetylglucosamine 2-epimeraseEC 5.1.3.14; Bacteriophage N4 adsorption protein C; UDP-GlcNAc-2-epimeraseEscherichia coli K-12
UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronate N-acetyltransferaseUDP-D-GlcNAc3NA N-acetyltransferase; EC 2.3.1.201; UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronic acid 3-N-acetyltransferasePseudomonas aeruginosa PAO1
UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidaseEC 1.1.1.335; UDP-2-acetamido-2-deoxy-alpha-D-glucuronic acid 3-dehydrogenase; UDP-N-acetyl-D-glucosaminuronic acid 3-oxidase; UDP-D-GlcNAcA 3-oxidasePseudomonas aeruginosa PAO1
UDP-2,3-diacetamido-2,3-dideoxy-D-glucuronate 2-epimeraseUDP-alpha-D-GlcNAc3NAcA 2-epimerase; EC 5.1.3.23; UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerasePseudomonas aeruginosa PAO1
UDP-N-acetyl-D-glucosamine 6-dehydrogenaseUDP-D-GlcNAc 6-dehydrogenase; EC 1.1.1.136; UDP-N-acetylglucosamine 6-dehydrogenasePseudomonas aeruginosa PAO1
UDP-galactose 4-epimerase
UDP-galactose 4-epimerase Pseudomonas aeruginosa
WbpGPseudomonas aeruginosa
Similar to UDP-N-acetylglucosamine2-epimerase Pseudomonas aeruginosa
NAD-dependent epimerase/dehydratase Pseudomonas aeruginosa
dTDP-4-dehydrorhamnose reductase
WbpMPseudomonas aeruginosa
ORF_17Pseudomonas aeruginosa
NAD-dependent dehydratase Pseudomonas aeruginosa
WbpPPseudomonas aeruginosa
UDP-glucose/GDP-mannose dehydrogenase-like protein Pseudomonas aeruginosa
UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferaseUDP-3-oxo-D-GlcNAcA aminotransferase; EC 2.6.1.98; UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronic acid transaminase; UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferasePseudomonas aeruginosa PAO1
UDP-N-acetylglucosamine 2-epimerase
Capsular biosynthesis protein Pseudomonas aeruginosa

Compounds (22)

CompoundDescription
diphosphoric acid
hydronium ion
NADH
Ammonium
Uridine TriphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
iodoacetamideAn alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
alpha-Ketoglutarate
diethyl pyrocarbonatePreservative for wines, soft drinks, and fruit juices and a gentle esterifying agent.
ethylmaleimideA sulfhydryl reagent that is widely used in experimental biochemical studies.
glucosamine 6-phosphateRN given refers to parent cpd
glutamate
Glucose-6-PhosphateAn ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
polyglutamineRN given for (D)-isomer
uridine diphosphate n-acetylmuramic acidA nucleoside diphosphate sugar which is formed from UDP-N-acetylglucosamine and phosphoenolpyruvate. It serves as the building block upon which peptidoglycan is formed.
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
2-deoxy-2-aminoglucitol-6-phosphateinhibits glucosamine 6-phosphate deaminase