Page last updated: 2024-10-06

superpathway of L-arginine and L-ornithine degradation

Proteins (13)

ProteinSynonymsTaxonomy
4-aminobutyrate aminotransferase GabTEC 2.6.1.19; 5-aminovalerate transaminase; 2.6.1.48; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminase; L-AIBATEscherichia coli K-12
Succinate-semialdehyde dehydrogenase [NADP(+)] GabDSSDH; EC 1.2.1.79; Glutarate-semialdehyde dehydrogenase; 1.2.1.-Escherichia coli K-12
Putrescine aminotransferasePAT; PATase; EC 2.6.1.82; Cadaverine transaminase; Diamine transaminase; 2.6.1.29; Putrescine transaminase; Putrescine--2-oxoglutaric acid transaminase; Putrescine:2-OG aminotransferaseEscherichia coli K-12
4-aminobutyrate aminotransferase PuuEEC 2.6.1.19; GABA aminotransferase; GABA-AT; Gamma-amino-N-butyrate transaminase; GABA transaminase; Glutamate:succinic semialdehyde transaminaseEscherichia coli K-12
Gamma-aminobutyraldehyde dehydrogenaseABALDH; EC 1.2.1.19; 1-pyrroline dehydrogenase; 4-aminobutanal dehydrogenase; 5-aminopentanal dehydrogenase; 1.2.1.-Escherichia coli K-12
Succinate semialdehyde dehydrogenase [NAD(P)+] SadSSADH; SSDH; EC 1.2.1.16Escherichia coli K-12
AgmatinaseEC 3.5.3.11; Agmatine ureohydrolase; AUHEscherichia coli K-12
Biodegradative arginine decarboxylaseADC; EC 4.1.1.19Escherichia coli K-12
Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuDGamma-Glu-GABA hydrolase; EC 3.5.1.94Escherichia coli K-12
NADP/NAD-dependent aldehyde dehydrogenase PuuCALDH; EC 1.2.1.5; 3-hydroxypropionaldehyde dehydrogenase; Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Gamma-Glu-gamma-aminobutyraldehyde dehydrogenaseEscherichia coli K-12
Inducible ornithine decarboxylaseEC 4.1.1.17Escherichia coli K-12
Gamma-glutamylputrescine oxidoreductaseGamma-Glu-Put oxidase; Gamma-glutamylputrescine oxidase; EC 1.4.3.-Escherichia coli K-12
Gamma-glutamylputrescine synthetase PuuAGamma-Glu-Put synthetase; EC 6.3.1.11; Glutamate--putrescine ligaseEscherichia coli K-12

Compounds (28)

CompoundDescription
hydronium ion
ureaA compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
ArginineAn essential amino acid that is physiologically active in the L-form.
Succinate
NADH
Ammonium
MercuryA silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
3-methylbenzaldehydestructure in first source
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
alpha-Ketoglutarate
Aminooxyacetate
ethylmaleimideA sulfhydryl reagent that is widely used in experimental biochemical studies.
Edetic AcidA chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
SpermidineA polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
hydroxylamineA colorless inorganic compound (HONH2) used in organic synthesis and as a reducing agent, due to its ability to donate nitric oxide.
phenylhydrazineRN given refers to parent cpd