Pathways > superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism
Page last updated: 2024-10-06

superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism

Proteins (20)

ProteinSynonymsTaxonomy
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2EC 3.1.3.86; Inositol polyphosphate phosphatase-like protein 1; INPPL-1; Protein 51C; SH2 domain-containing inositol 5'-phosphatase 2; SH2 domain-containing inositol phosphatase 2; SHIP-2Homo sapiens (human)
Inositol-trisphosphate 3-kinase AEC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase AHomo sapiens (human)
Inositol polyphosphate multikinaseEC 2.7.1.140; EC 2.7.1.151; EC 2.7.1.153; Inositol 1,3,4,6-tetrakisphosphate 5-kinaseHomo sapiens (human)
Type II inositol 1,4,5-trisphosphate 5-phosphataseEC 3.1.3.36; 75 kDa inositol polyphosphate-5-phosphatase; Phosphoinositide 5-phosphatase; 5PTaseHomo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENEC 3.1.3.16; EC 3.1.3.48; EC 3.1.3.67; Mutated in multiple advanced cancers 1; Phosphatase and tensin homologHomo sapiens (human)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 EC 3.1.3.86; Inositol polyphosphate-5-phosphatase D; 3.1.3.56; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; Phosphatidylinositol 4,5-bisphosphate 5-phosphatase; 3.1.3.36; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing Homo sapiens (human)
Synaptojanin-2EC 3.1.3.36; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2Homo sapiens (human)
Synaptojanin-1EC 3.1.3.36; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1Homo sapiens (human)
Inositol polyphosphate-5-phosphatase AEC 3.1.3.56; 43 kDa inositol polyphosphate 5-phosphatase; Type I inositol 1,4,5-trisphosphate 5-phosphatase; 5PTaseHomo sapiens (human)
Inositol polyphosphate multikinaseIPMK; EC 2.7.1.151; Arginine metabolism regulation protein IIISaccharomyces cerevisiae S288C
Inositol-trisphosphate 3-kinase BEC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase B; IP3 3-kinase B; IP3K B; InsP 3-kinase BHomo sapiens (human)
Inositol polyphosphate 5-phosphatase KEC 3.1.3.56; Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase; 3.1.3.86; Phosphatidylinositol-4,5-bisphosphate 5-phosphatase; 3.1.3.36; Skeletal muscle and kidney-enriched inositol phosphataseHomo sapiens (human)
Inositol polyphosphate 1-phosphataseIPP; IPPase; EC 3.1.3.57Homo sapiens (human)
Inositol monophosphatase 2IMP 2; IMPase 2; EC 3.1.3.25; Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2Homo sapiens (human)
Inositol monophosphatase 1IMP 1; IMPase 1; EC 3.1.3.25; D-galactose 1-phosphate phosphatase; 3.1.3.94; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1Homo sapiens (human)
Inositol polyphosphate 5-phosphatase OCRLEC 3.1.3.36; EC 3.1.3.56; Inositol polyphosphate 5-phosphatase OCRL-1; OCRL-1; Lowe oculocerebrorenal syndrome protein; Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase; 3.1.3.86Homo sapiens (human)
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase AEC 3.1.3.56; Inositol polyphosphate 5-phosphatase JHomo sapiens (human)
Inositol-trisphosphate 3-kinase CEC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase C; IP3 3-kinase C; IP3K C; InsP 3-kinase CHomo sapiens (human)
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphataseGolgi-resident PAP phosphatase; gPAPP; EC 3.1.3.7; 3'(2'), 5'-bisphosphate nucleotidase 2; Inositol monophosphatase domain-containing protein 1; Myo-inositol monophosphatase A3; Phosphoadenosine phosphate 3'-nucleotidaseHomo sapiens (human)
Multiple inositol polyphosphate phosphatase 1EC 3.1.3.62; 2,3-bisphosphoglycerate 3-phosphatase; 2,3-BPG phosphatase; 3.1.3.80; Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; Ins(1,3,4,5)P(4) 3-phosphataseHomo sapiens (human)

Compounds (11)

CompoundDescription
hydronium ion
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
inositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Nalidixic AcidA synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.
inositol 1,3,4-trisphosphate
inositol 1,4-bis(phosphate)induced in human platelets by thrombin; RN given refers to cpd without isomeric designation