Page last updated: 2024-10-06

superpathway of Clostridium acetobutylicum solventogenic fermentation

Proteins (14)

ProteinSynonymsTaxonomy
Acetoacetate decarboxylaseAAD; ADC; EC 4.1.1.4Clostridium acetobutylicum ATCC 824
3-hydroxybutyryl-CoA dehydrogenaseEC 1.1.1.157; Beta-hydroxybutyryl-CoA dehydrogenase; BHBDClostridium acetobutylicum ATCC 824
Acyl-CoA dehydrogenase, short-chain specificEC 1.3.8.1; Butyryl-CoA dehydrogenase; SCADClostridium acetobutylicum ATCC 824
Short-chain-enoyl-CoA hydrataseEC 4.2.1.150; 3-hydroxybutyryl-CoA dehydratase; CrotonaseClostridium acetobutylicum ATCC 824
Acetyl-CoA acetyltransferaseEC 2.3.1.9; Acetoacetyl-CoA thiolaseClostridium acetobutylicum ATCC 824
Butyrate--acetoacetate CoA-transferase subunit BCoat B; EC 2.8.3.9; Acetoacetyl-CoA:acetate/butyrate CoA-transferase subunit BClostridium acetobutylicum ATCC 824
Butyrate--acetoacetate CoA-transferase subunit ACoat A; EC 2.8.3.9; Acetoacetyl-CoA:acetate/butyrate:CoA transferase subunit AClostridium acetobutylicum ATCC 824
NADPH-dependent butanol dehydrogenaseBDH; EC 1.1.1.-Clostridium saccharobutylicum
Aldehyde-alcohol dehydrogenaseAADClostridium acetobutylicum ATCC 824
NADH-dependent butanol dehydrogenase AEC 1.1.1.-; BDH IClostridium acetobutylicum ATCC 824
NADH-dependent butanol dehydrogenase BEC 1.1.1.-; BDH IIClostridium acetobutylicum ATCC 824
3-hydroxybutyryl-CoA dehydrogenase Clostridium beijerinckii
Aldehyde-alcohol dehydrogenaseClostridium acetobutylicum
Pyruvate:ferredoxin oxidoreductaseClostridium acetobutylicum ATCC 824

Compounds (34)

CompoundDescription
1-propanolA colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.
hydronium ion
n-Butyrate
Thiamine PyrophosphateThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
NADH
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
EthanolA clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
iodoacetamideAn alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate.
benzoylacetone
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
1,10-phenanthrolineRN given refers to parent cpd; inhibits Zn-dependent metalloproteinases
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
acetaldehydeA colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
acetoneA colorless liquid used as a solvent and an antiseptic. It is one of the ketone bodies produced during ketoacidosis.
butyraldehyde
1-butanolA four carbon linear hydrocarbon that has a hydroxy group at position 1.
Sodium Dodecyl SulfateAn anionic surfactant, usually a mixture of sodium alkyl sulfates, mainly the lauryl; lowers surface tension of aqueous solutions; used as fat emulsifier, wetting agent, detergent in cosmetics, pharmaceuticals and toothpastes; also as research tool in protein biochemistry.
acetopyruvate
4-ChloromercuribenzenesulfonateA cytotoxic sulfhydryl reagent that inhibits several subcellular metabolic systems and is used as a tool in cellular physiology.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
methylethyl ketonesolvent; colorless synthetic resins, smokeless powders; may be irritating to eyes, mucous membranes; may be toxic in high concentrations; structure
acetoacetate
hydrogen cyanideHydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
Coenzyme A
sapropterinRN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
acetylacetone
acetoacetyl CoA
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
4,7-phenanthroline