| Protein | Synonyms | Taxonomy |
|---|
| N-acylneuraminate-9-phosphatase | EC 3.1.3.29; Haloacid dehalogenase-like hydrolase domain-containing protein 4; Neu5Ac-9-Pase | Homo sapiens (human) |
| N-acylneuraminate cytidylyltransferase | EC 2.7.7.43; CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase | Mus musculus (house mouse) |
| N-acylneuraminate cytidylyltransferase | EC 2.7.7.43; CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase | Escherichia coli |
| N-acylneuraminate cytidylyltransferase | EC 2.7.7.43; CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase | Rattus norvegicus (Norway rat) |
| N-acylneuraminate cytidylyltransferase | EC 2.7.7.43; CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase | Oncorhynchus mykiss (rainbow trout) |
| NADH-cytochrome b5 reductase 3 | B5R; Cytochrome b5 reductase; EC 1.6.2.2; Diaphorase-1 | Mus musculus (house mouse) |
| N-acylneuraminate-9-phosphatase | EC 3.1.3.29; Haloacid dehalogenase-like hydrolase domain-containing protein 4; Neu5Ac-9-Pase | Rattus norvegicus (Norway rat) |
| Polysialic acid biosynthesis protein P7 | | Escherichia coli |
| Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase | UDP-GlcNAc-2-epimerase/ManAc kinase | Rattus norvegicus (Norway rat) |
| Cytidine monophosphate-N-acetylneuraminic acid hydroxylase | CMP-N-acetylneuraminic acid hydroxylase; EC 1.14.18.2; CMP-N-acetylneuraminate monooxygenase; CMP-Neu5Ac hydroxylase; CMP-NeuAc hydroxylase | Mus musculus (house mouse) |
| Sialic acid synthase | N-acetylneuraminate-9-phosphate synthase; 2.5.1.57; N-acetylneuraminic acid phosphate synthase | Mus musculus (house mouse) |
| Sialic acid synthase | N-acetylneuraminate synthase; 2.5.1.56; N-acetylneuraminate-9-phosphate synthase; 2.5.1.57; N-acetylneuraminic acid phosphate synthase; N-acetylneuraminic acid synthase | Homo sapiens (human) |
| Putative sialic acid synthase NeuB | | Aliivibrio salmonicida LFI1238 |
| N,N'-diacetyllegionaminic acid synthase | | Escherichia coli |
| Compound | Description |
|---|
| diphosphoric acid | |
| hydronium ion | |
| Cobalt | A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. |
| Silver | An element with the atomic symbol Ag, atomic number 47, and atomic weight 107.87. It is a soft metal that is used medically in surgical instruments, dental prostheses, and alloys. Long-continued use of silver salts can lead to a form of poisoning known as ARGYRIA. |
| uridine diphosphate | A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. |
| Mercury | A silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing. |
| Copper | A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Manganese | A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035) |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| Sodium Chloride | A ubiquitous sodium salt that is commonly used to season food. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Uridine Triphosphate | Uridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety. |
| iodine | A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Nickel | A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| cmp-deaminoneuraminic acid | |
| thymidine 5'-triphosphate | RN given refers to parent cpd |
| 1,10-phenanthroline | RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases |
| mercaptoethanol | A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation. |
| mannose | A hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants. (From Grant & Hackh's Chemical Dictionary, 5th ed & Random House Unabridged Dictionary, 2d ed) |
| ethylmaleimide | A sulfhydryl reagent that is widely used in experimental biochemical studies. |
| dithiothreitol | A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols. |
| carbamylhydrazine | RN given refers to parent cpd |
| Edetic Acid | A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive. |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| ammonium sulfate | Sulfuric acid diammonium salt. It is used in CHEMICAL FRACTIONATION of proteins. |
| vanadates | Oxyvanadium ions in various states of oxidation. They act primarily as ion transport inhibitors due to their inhibition of Na(+)-, K(+)-, and Ca(+)-ATPase transport systems. They also have insulin-like action, positive inotropic action on cardiac ventricular muscle, and other metabolic effects. |
| bromosuccinimide | A brominating agent that replaces hydrogen atoms in benzylic or allylic positions. It is used in the oxidation of secondary alcohols to ketones and in controlled low-energy brominations. (From Miall's Dictionary of Chemistry, 5th ed; Hawley's Condensed Chemical Dictionary, 12th ed,). |
| Cytidine Monophosphate | Cytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. |
| Cytidine Triphosphate | Cytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety. |
| hydroxylamine | A colorless inorganic compound (HONH2) used in organic synthesis and as a reducing agent, due to its ability to donate nitric oxide. |
| Cytidine Diphosphate | Cytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate. |
| Coenzyme A | |
| Acetyl Coenzyme A | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| 2-acetamido-2-deoxy-mannose-6-phosphate | structure in first source |