Page last updated: 2024-10-06

superpathway NAD/NADP - NADH/NADPH interconversion (yeast)

Proteins (10)

ProteinSynonymsTaxonomy
ATP-NADH kinase YEF1EC 2.7.1.86Saccharomyces cerevisiae S288C
NADH kinase POS5, mitochondrialEC 2.7.1.86Saccharomyces cerevisiae S288C
Magnesium-activated aldehyde dehydrogenase, cytosolicEC 1.2.1.4; Mg(2+)-activated acetaldehyde dehydrogenase; Mg(2+)-ACDHSaccharomyces cerevisiae S288C
Glucose-6-phosphate 1-dehydrogenaseG6PD; EC 1.1.1.49Saccharomyces cerevisiae S288C
NAD(+) kinaseEC 2.7.1.23; Unknown transcript 1 proteinSaccharomyces cerevisiae S288C
Isocitrate dehydrogenase [NADP] cytoplasmicIDH; EC 1.1.1.42; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylaseSaccharomyces cerevisiae S288C
Aldehyde dehydrogenase 5, mitochondrialEC 1.2.1.5Saccharomyces cerevisiae S288C
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrialEC 1.6.5.9; Internal NADH dehydrogenase; NADH:ubiquinone reductase (non-electrogenic)Saccharomyces cerevisiae S288C
External NADH-ubiquinone oxidoreductase 1, mitochondrialEC 1.6.5.9; External NADH dehydrogenase 1Saccharomyces cerevisiae S288C
External NADH-ubiquinone oxidoreductase 2, mitochondrialEC 1.6.5.9; External NADH dehydrogenase 2Saccharomyces cerevisiae S288C

Compounds (28)

CompoundDescription
hydronium ion
CobaltA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
flavoneRN given refers to unlabeled cpd; structure given in first source
NADH
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
LithiumAn element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
ubiquinol 1
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
alpha-Ketoglutarate
acetaldehydeA colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
ubiquinone q1interacts with iron atom to form acceptor quinone complex
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Glucose-6-PhosphateAn ester of glucose with phosphoric acid, made in the course of glucose metabolism by mammalian and other cells. It is a normal constituent of resting muscle and probably is in constant equilibrium with fructose-6-phosphate. (Stedman, 26th ed)
mercuric chlorideMercury chloride (HgCl2). A highly toxic compound that volatizes slightly at ordinary temperature and appreciably at 100 degrees C. It is corrosive to mucous membranes and used as a topical antiseptic and disinfectant.
6-phosphogluconolactonean electrophilic compound