Page last updated: 2024-10-06
staurosporine biosynthesis
Proteins (8)
| Protein | Synonyms | Taxonomy |
|---|
| Cytochrome P450 | | Streptomyces sp. TP-A0274 |
| L-amino acid oxidase | | Streptomyces sp. TP-A0274 |
| Methyltransferase | | Streptomyces sp. TP-A0274 |
| Methyltransferase | | Streptomyces sp. TP-A0274 |
| N-glycosyltransferase | | Streptomyces sp. TP-A0274 |
| Cytochrome P450 StaN | | Streptomyces sp. TP-A0274 |
| Monooxygenase | | Streptomyces sp. TP-A0274 |
| Chromopyrrolic acid synthase StaD | | Streptomyces sp. TP-A0274 |
Compounds (13)
| Compound | Description |
|---|
| hydronium ion | |
| NADH | |
| Ammonium | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| staurosporine aglycone | metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor |
| staurosporine | An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20) |
| thymidine 5'-diphosphate | see also record for thymidine 3',5'-diphosphate, RN 2863-04-9 |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |