| Protein | Synonyms | Taxonomy |
|---|
| Inositol phosphorylceramide synthase catalytic subunit AUR1 | IPC synthase catalytic subunit AUR1; EC 2.-.-.-; Aureobasidin A resistance protein; Phosphatidylinositol:ceramide phosphoinositol transferase | Saccharomyces cerevisiae S288C |
| Serine palmitoyltransferase 1 | SPT 1; SPT1; EC 2.3.1.50; Long chain base biosynthesis protein 1 | Saccharomyces cerevisiae S288C |
| Serine palmitoyltransferase 2 | SPT 2; EC 2.3.1.50; Long chain base biosynthesis protein 2 | Saccharomyces cerevisiae S288C |
| 3-ketodihydrosphingosine reductase TSC10 | EC 1.1.1.102; 3-dehydrosphinganine reductase; KDS reductase; Temperature-sensitive CSG2 suppressor protein 10 | Saccharomyces cerevisiae S288C |
| Ceramide synthase LAC1 | EC 2.3.1.-; Sphingosine N-acyltransferase LAC1; 2.3.1.24 | Saccharomyces cerevisiae S288C |
| Mannosyl phosphorylinositol ceramide synthase SUR1 | EC 2.4.-.- | Saccharomyces cerevisiae S288C |
| Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2 | | Saccharomyces cerevisiae S288C |
| Mannosyl phosphorylinositol ceramide synthase CSH1 | EC 2.-.-.-; CSG1/SUR1 homolog 1 | Saccharomyces cerevisiae S288C |
| Ceramide synthase LAG1 | EC 2.3.1.-; Longevity assurance factor 1; Longevity assurance gene 1 protein; Longevity assurance protein 1; Sphingosine N-acyltransferase LAG1; 2.3.1.24 | Saccharomyces cerevisiae S288C |
| Inositolphosphotransferase 1 | EC 2.7.1.228; Mannosyl diphosphorylinositol ceramide synthase | Saccharomyces cerevisiae S288C |
| Sphingolipid C4-hydroxylase SUR2 | EC 1.-.-.-; Syringomycin response protein 2 | Saccharomyces cerevisiae S288C |
| Ceramide very long chain fatty acid hydroxylase SCS7 | Ceramide VLCFA hydroxylase SCS7; 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7; 1.14.18.6; Dihydroceramide fatty acyl 2-hydroxylase SCS7; 1.14.18.7; Sphingolipid alpha-hydroxylase; Suppressor of calcium sensitivity 7 | Saccharomyces cerevisiae S288C |
| Ceramide synthase subunit LIP1 | LAG1/LAC1-interacting protein 1 | Saccharomyces cerevisiae S288C |
| Inositol phosphorylceramide synthase regulatory subunit KEI1 | ICP synthase regulatory subunit KEI1; KEX2-cleavable protein essential for inositol phosphorylceramide synthesis | Saccharomyces cerevisiae S288C |
| Compound | Description |
|---|
| hydronium ion | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| phytosphingosine | differ with an additional hydroxyl at C-4 & no double bond between C-4 & C-5 |
| r-106 | |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| Coenzyme A | |
| Palmitoyl Coenzyme A | A fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis. |
| sphinganine | |
| fumonisin B1 | isolated from Fusarium moniliforme MRC 826; structure given in first source; has cancer-promoting activity; inhibits ceramide synthase |