Pathways > sphingolipid biosynthesis (yeast)
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sphingolipid biosynthesis (yeast)

Proteins (14)

ProteinSynonymsTaxonomy
Inositol phosphorylceramide synthase catalytic subunit AUR1IPC synthase catalytic subunit AUR1; EC 2.-.-.-; Aureobasidin A resistance protein; Phosphatidylinositol:ceramide phosphoinositol transferaseSaccharomyces cerevisiae S288C
Serine palmitoyltransferase 1SPT 1; SPT1; EC 2.3.1.50; Long chain base biosynthesis protein 1Saccharomyces cerevisiae S288C
Serine palmitoyltransferase 2SPT 2; EC 2.3.1.50; Long chain base biosynthesis protein 2Saccharomyces cerevisiae S288C
3-ketodihydrosphingosine reductase TSC10EC 1.1.1.102; 3-dehydrosphinganine reductase; KDS reductase; Temperature-sensitive CSG2 suppressor protein 10Saccharomyces cerevisiae S288C
Ceramide synthase LAC1EC 2.3.1.-; Sphingosine N-acyltransferase LAC1; 2.3.1.24Saccharomyces cerevisiae S288C
Mannosyl phosphorylinositol ceramide synthase SUR1EC 2.4.-.-Saccharomyces cerevisiae S288C
Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2Saccharomyces cerevisiae S288C
Mannosyl phosphorylinositol ceramide synthase CSH1EC 2.-.-.-; CSG1/SUR1 homolog 1Saccharomyces cerevisiae S288C
Ceramide synthase LAG1EC 2.3.1.-; Longevity assurance factor 1; Longevity assurance gene 1 protein; Longevity assurance protein 1; Sphingosine N-acyltransferase LAG1; 2.3.1.24Saccharomyces cerevisiae S288C
Inositolphosphotransferase 1EC 2.7.1.228; Mannosyl diphosphorylinositol ceramide synthaseSaccharomyces cerevisiae S288C
Sphingolipid C4-hydroxylase SUR2EC 1.-.-.-; Syringomycin response protein 2Saccharomyces cerevisiae S288C
Ceramide very long chain fatty acid hydroxylase SCS7Ceramide VLCFA hydroxylase SCS7; 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase SCS7; 1.14.18.6; Dihydroceramide fatty acyl 2-hydroxylase SCS7; 1.14.18.7; Sphingolipid alpha-hydroxylase; Suppressor of calcium sensitivity 7Saccharomyces cerevisiae S288C
Ceramide synthase subunit LIP1LAG1/LAC1-interacting protein 1Saccharomyces cerevisiae S288C
Inositol phosphorylceramide synthase regulatory subunit KEI1ICP synthase regulatory subunit KEI1; KEX2-cleavable protein essential for inositol phosphorylceramide synthesisSaccharomyces cerevisiae S288C

Compounds (12)

CompoundDescription
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
phytosphingosinediffer with an additional hydroxyl at C-4 & no double bond between C-4 & C-5
r-106
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Coenzyme A
Palmitoyl Coenzyme AA fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis.
sphinganine
fumonisin B1isolated from Fusarium moniliforme MRC 826; structure given in first source; has cancer-promoting activity; inhibits ceramide synthase
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