Page last updated: 2024-10-06

sphingolipid biosynthesis (plants)

Proteins (12)

ProteinSynonymsTaxonomy
3-dehydrosphinganine reductase TSC10AEC 1.1.1.102; 3-ketodihydrosphingosine reductase; KDS reductase; 3-ketosphinganine reductaseArabidopsis thaliana (thale cress)
Long chain base biosynthesis protein 1AtLCB1; EC 2.3.1.50; Protein EMBRYO DEFECTIVE 2779; Protein FUMONISIN B1 RESISTANT 11Arabidopsis thaliana (thale cress)
Long chain base biosynthesis protein 2aAtLCB2a; EC 2.3.1.50; Long chain base biosynthesis protein 2; AtLCB2Arabidopsis thaliana (thale cress)
Ceramide kinaseAtCERK; EC 2.7.1.138; Protein ACCELERATED CELL DEATH 5Arabidopsis thaliana (thale cress)
Sphingolipid delta(4)-desaturase DES1-likeEC 1.14.19.17Arabidopsis thaliana (thale cress)
Protein ASC1Alternaria stem canker resistance protein 1Solanum lycopersicum (tomato)
Dihydroceramide fatty acyl 2-hydroxylase FAH1EC 1.14.18.7; Fatty acid 2-hydroxylase 1; AtFAH1Arabidopsis thaliana (thale cress)
Sphingosine kinase 1EC 2.7.1.91Arabidopsis thaliana (thale cress)
Sphinganine C4-monooxygenase 1EC 1.14.18.5; Sphingoid C4-hydroxylase 1; Sphingoid base hydroxylase 1Arabidopsis thaliana (thale cress)
Sphinganine C4-monooxygenase 2EC 1.14.18.5; Sphingoid C4-hydroxylase 2; Sphingoid base hydroxylase 2Arabidopsis thaliana (thale cress)
Phosphatidylinositol:ceramide inositolphosphotransferase 2EC 2.7.8.-; Inositol-phosphorylceramide synthase 2; AtIPCS2; IPC synthase 2; Protein ENHANCING RPW8-MEDIATED HR-LIKE CELL DEATH 1; Sphingolipid synthase 2Arabidopsis thaliana (thale cress)
Delta(8)-fatty-acid desaturase 1EC 1.14.19.29; Delta(8)-sphingolipid desaturase 1; Sphingoid long-chain base desaturase 1; Sphingoid LCB desaturase 1; Sphingolipid 8-(E/Z)-desaturase 1Arabidopsis thaliana (thale cress)

Compounds (20)

CompoundDescription
hydronium ion
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
phytosphingosinediffer with an additional hydroxyl at C-4 & no double bond between C-4 & C-5
r-106
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
rustmicinactive against wheat stem rust fungus; isolated from Streptomyces galbus Micromonospora narashinoensis 980-MC1; MF C21-H32-O6; structure given in first source; also isolated from Streptomyces galbus
beta-chloro-D-alanine
Coenzyme A
Palmitoyl Coenzyme AA fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis.
sphinganine
dihydrosphingosine 1-phosphateRN given refers to (R-(R*,S*))-isomer
dihydroceramidelacks the 4-5 trans double bond of the sphingosine moiety of ceramides; structure in first source