rRNA modification in the nucleus and cytosol

Proteins (58)

Protein	Synonyms	Taxonomy
Ribosomal RNA small subunit methyltransferase NEP1	EC 2.1.1.-; 18S rRNA (pseudouridine(1248)-N1)-methyltransferase; 18S rRNA Psi1248 methyltransferase; Nucleolar protein EMG1 homolog; Protein C2f; Ribosome biogenesis protein NEP1	Homo sapiens (human)
RNA cytidine acetyltransferase	EC 2.3.1.-; 18S rRNA cytosine acetyltransferase; N-acetyltransferase 10; N-acetyltransferase-like protein; hALP	Homo sapiens (human)
Something about silencing protein 10	Charged amino acid-rich leucine zipper 1; CRL1; Disrupter of silencing SAS10; UTP3 homolog	Homo sapiens (human)
40S ribosomal protein S2	40S ribosomal protein S4; Protein LLRep3; Small ribosomal subunit protein uS5	Homo sapiens (human)
40S ribosomal protein S9	Small ribosomal subunit protein uS4	Homo sapiens (human)
40S ribosomal protein S7	Small ribosomal subunit protein eS7	Homo sapiens (human)
40S ribosomal protein S14	Small ribosomal subunit protein uS11	Homo sapiens (human)
40S ribosomal protein S6	Phosphoprotein NP33; Small ribosomal subunit protein eS6	Homo sapiens (human)
Nucleolar protein 6	Nucleolar RNA-associated protein; Nrap	Homo sapiens (human)
Multifunctional methyltransferase subunit TRM112-like protein	tRNA methyltransferase 112 homolog	Homo sapiens (human)
U3 small nucleolar ribonucleoprotein protein MPP10	M phase phosphoprotein 10	Homo sapiens (human)
Nucleolar protein 56	Nucleolar protein 5A	Homo sapiens (human)
WD repeat-containing protein 46	WD repeat-containing protein BING4	Homo sapiens (human)
Probable 18S rRNA (guanine-N(7))-methyltransferase	EC 2.1.1.-; Bud site selection protein 23 homolog; Metastasis-related methyltransferase 1; Williams-Beuren syndrome chromosomal region 22 protein; rRNA methyltransferase and ribosome maturation factor	Homo sapiens (human)
U3 small nucleolar RNA-interacting protein 2	RRP9 homolog; U3 small nucleolar ribonucleoprotein-associated 55 kDa protein; U3 snoRNP-associated 55 kDa protein; U3-55K	Homo sapiens (human)
H/ACA ribonucleoprotein complex subunit DKC1	EC 5.4.99.-; CBF5 homolog; Dyskerin; Nopp140-associated protein of 57 kDa; Nucleolar protein NAP57; Nucleolar protein family A member 4; snoRNP protein DKC1	Homo sapiens (human)
Small subunit processome component 20 homolog	Down-regulated in metastasis protein; Novel nucleolar protein 73; NNP73; Protein Key-1A6	Homo sapiens (human)
rRNA 2'-O-methyltransferase fibrillarin	EC 2.1.1.-; 34 kDa nucleolar scleroderma antigen; Histone-glutamine methyltransferase; U6 snRNA 2'-O-methyltransferase fibrillarin	Homo sapiens (human)
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase	EC 2.1.1.-; Nucleolar protein 1; Nucleolar protein 2 homolog; Proliferating-cell nucleolar antigen p120; Proliferation-associated nucleolar protein p120	Homo sapiens (human)
NHP2-like protein 1	High mobility group-like nuclear protein 2 homolog 1; OTK27; SNU13 homolog; hSNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 tri-snRNP 15.5 kDa protein	Homo sapiens (human)
Nucleolar protein 14	Nucleolar complex protein 14	Homo sapiens (human)
Transducin beta-like protein 3	WD repeat-containing protein SAZD	Homo sapiens (human)
KRR1 small subunit processome component homolog	HIV-1 Rev-binding protein 2; KRR-R motif-containing protein 1; Rev-interacting protein 1; Rip-1	Homo sapiens (human)
Protein RRP5 homolog	NF-kappa-B-binding protein; NFBP; Programmed cell death protein 11	Homo sapiens (human)
Ribosome biogenesis protein BMS1 homolog	Ribosome assembly protein BMS1 homolog	Homo sapiens (human)
WD repeat-containing protein 43	U3 small nucleolar RNA-associated protein 5 homolog	Homo sapiens (human)
Periodic tryptophan protein 2 homolog		Homo sapiens (human)
Digestive organ expansion factor homolog		Homo sapiens (human)
WD repeat-containing protein 75	U3 small nucleolar RNA-associated protein 17 homolog	Homo sapiens (human)
Probable ATP-dependent RNA helicase DHX37	EC 3.6.4.13; DEAH box protein 37	Homo sapiens (human)
WD repeat-containing protein 36	T-cell activation WD repeat-containing protein; TA-WDRP	Homo sapiens (human)
U3 small nucleolar RNA-associated protein 15 homolog		Homo sapiens (human)
U3 small nucleolar RNA-associated protein 4 homolog	Cirhin; UTP4 small subunit processome component	Homo sapiens (human)
Ribosomal RNA processing protein 36 homolog		Homo sapiens (human)
U3 small nucleolar ribonucleoprotein protein IMP4	U3 snoRNP protein IMP4; Brix domain-containing protein 4	Homo sapiens (human)
Nucleolar complex protein 4 homolog	NOC4 protein homolog; NOC4-like protein; Nucleolar complex-associated protein 4-like protein	Homo sapiens (human)
Probable ATP-dependent RNA helicase DDX47	EC 3.6.4.13; DEAD box protein 47	Homo sapiens (human)
HEAT repeat-containing protein 1	Protein BAP28; U3 small nucleolar RNA-associated protein 10 homolog	Homo sapiens (human)
Nucleolar protein 11		Homo sapiens (human)
H/ACA ribonucleoprotein complex subunit 3	Nucleolar protein 10; Nucleolar protein family A member 3; snoRNP protein NOP10	Homo sapiens (human)
RNA-binding protein PNO1	Partner of NOB1	Homo sapiens (human)
DDB1- and CUL4-associated factor 13	WD repeat and SOF domain-containing protein 1	Homo sapiens (human)
U3 small nucleolar ribonucleoprotein protein IMP3	U3 snoRNP protein IMP3; BRMS2	Homo sapiens (human)
H/ACA ribonucleoprotein complex subunit 2	Nucleolar protein family A member 2; snoRNP protein NHP2	Homo sapiens (human)
THUMP domain-containing protein 1		Homo sapiens (human)
H/ACA ribonucleoprotein complex subunit 1	Nucleolar protein family A member 1; snoRNP protein GAR1	Homo sapiens (human)
U3 small nucleolar RNA-associated protein 6 homolog	Hepatocellular carcinoma-associated antigen 66; Multiple hat domains protein	Homo sapiens (human)
18S rRNA aminocarboxypropyltransferase	EC 2.5.1.-; 20S S rRNA accumulation protein 3 homolog; HsTsr3	Homo sapiens (human)
Probable dimethyladenosine transferase	EC 2.1.1.183; DIM1 dimethyladenosine transferase 1 homolog; DIM1 dimethyladenosine transferase 1-like; Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase; Probable 18S rRNA dimethylase; Probable S-adenosylmethionine-6-N',N'-aden	Homo sapiens (human)
WD repeat-containing protein 3		Homo sapiens (human)
RNA 3'-terminal phosphate cyclase-like protein		Homo sapiens (human)
Probable ATP-dependent RNA helicase DDX52	EC 3.6.4.13; ATP-dependent RNA helicase ROK1-like; DEAD box protein 52	Homo sapiens (human)
Nucleolar protein 58	Nucleolar protein 5	Homo sapiens (human)
rRNA-processing protein FCF1 homolog		Homo sapiens (human)
Probable U3 small nucleolar RNA-associated protein 11	U3 snoRNA-associated protein 11; UTP11-like protein	Homo sapiens (human)
Ribosomal RNA-processing protein 7 homolog A	Gastric cancer antigen Zg14	Homo sapiens (human)
U3 small nucleolar RNA-associated protein 18 homolog	WD repeat-containing protein 50	Homo sapiens (human)
Probable ATP-dependent RNA helicase DDX49	EC 3.6.4.13; DEAD box protein 49	Homo sapiens (human)

Compounds (7)

Compound	Description
Orthophosphate
adenosine diphosphate	Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
5'-methylthioadenosine	structure
adenosine triphosphate	An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-adenosylmethionine	Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Coenzyme A
Acetyl Coenzyme A	Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.