Page last updated: 2024-10-06

pyruvate to cytochrome bo oxidase electron transfer

Proteins (5)

ProteinSynonymsTaxonomy
Pyruvate dehydrogenase [ubiquinone]EC 1.2.5.1; Pyruvate oxidase; POX; Pyruvate:ubiquinone-8 oxidoreductaseEscherichia coli K-12
Cytochrome bo(3) ubiquinol oxidase subunit 1EC 7.1.1.3; Cytochrome b562-o complex subunit I; Cytochrome o ubiquinol oxidase subunit 1; Cytochrome o subunit 1; Oxidase bo(3) subunit 1; Ubiquinol oxidase chain A; Ubiquinol oxidase polypeptide I; Ubiquinol oxidase subunit 1Escherichia coli K-12
Cytochrome bo(3) ubiquinol oxidase subunit 2Cytochrome b562-o complex subunit II; Cytochrome o ubiquinol oxidase subunit 2; Cytochrome o subunit 2; Oxidase bo(3) subunit 2; Ubiquinol oxidase chain B; Ubiquinol oxidase polypeptide II; Ubiquinol oxidase subunit 2Escherichia coli K-12
Cytochrome bo(3) ubiquinol oxidase subunit 3Cytochrome o ubiquinol oxidase subunit 3; Cytochrome o subunit 3; Oxidase bo(3) subunit 3; Ubiquinol oxidase chain C; Ubiquinol oxidase polypeptide III; Ubiquinol oxidase subunit 3Escherichia coli K-12
Cytochrome bo(3) ubiquinol oxidase subunit 4Cytochrome o ubiquinol oxidase subunit 4; Cytochrome o subunit 4; Oxidase bo(3) subunit 4; Ubiquinol oxidase chain D; Ubiquinol oxidase polypeptide IV; Ubiquinol oxidase subunit 4Escherichia coli K-12

Compounds (32)

CompoundDescription
diphosphoric acid
hydronium ion
CobaltA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
Nitric OxideA free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
Thiamine PyrophosphateThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
hydrogen sulfideA flammable, poisonous gas with a characteristic odor of rotten eggs. It is used in the manufacture of chemicals, in metallurgy, and as an analytical reagent. (From Merck Index, 11th ed)
ubiquinol 1
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
phenylglyoxalA reagent that is highly selective for the modification of arginyl residues. It is used to selectively inhibit various enzymes and acts as an energy transfer inhibitor in photophosphorylation.
2-(n-heptyl)-4-hydroxyquinoline n-oxidestructure
hydrazoic acid
CadmiumAn element with atomic symbol Cd, atomic number 48, and atomic weight 112.41. It is a metal and ingestion will lead to CADMIUM POISONING.
ethylmaleimideA sulfhydryl reagent that is widely used in experimental biochemical studies.
ubiquinone q1interacts with iron atom to form acceptor quinone complex
dimethylformamideA formamide in which the amino hydrogens are replaced by methyl groups.
piericidin apyridine-substituted fatty alcohol antibiotic; minor descriptor (75-85); on-line & Index Medicus search ANTIBIOTICS (75-85); RN given refers to (S-(R*,R*-(all-E)))-isomer
diacetylCarrier of aroma of butter, vinegar, coffee, and other foods.
hydroxylamineA colorless inorganic compound (HONH2) used in organic synthesis and as a reducing agent, due to its ability to donate nitric oxide.
potassium cyanideA highly poisonous compound that is an inhibitor of many metabolic processes, but has been shown to be an especially potent inhibitor of heme enzymes and hemeproteins. It is used in many industrial processes.
methyl methanethiosulfonate
phosphonoacetaldehyde
dimethylacetamide
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
hemeThe color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins.
formamide
methylacetylphosphonateinhibitor of pyruvate dehydrogenase complex, don't confuse with methyl acetylphosphonate