Page last updated: 2024-10-06

pyruvate fermentation to hexanol (engineered)

Proteins (8)

ProteinSynonymsTaxonomy
3-hydroxybutyryl-CoA dehydrogenaseEC 1.1.1.157; Beta-hydroxybutyryl-CoA dehydrogenase; BHBDClostridium acetobutylicum ATCC 824
Short-chain-enoyl-CoA hydrataseEC 4.2.1.150; 3-hydroxybutyryl-CoA dehydratase; CrotonaseClostridium acetobutylicum ATCC 824
Acetyl-CoA acetyltransferaseEC 2.3.1.9; Acetoacetyl-CoA thiolaseEscherichia coli K-12
Beta-ketothiolase BktBEC 2.3.1.16; EC 2.3.1.9; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferaseCupriavidus necator H16
Trans-2-enoyl-CoA reductase, mitochondrialEC 1.3.1.44Euglena gracilis
3-hydroxybutyryl-CoA dehydrogenase Clostridium beijerinckii
Aldehyde-alcohol dehydrogenaseClostridium acetobutylicum
Pyruvate:ferredoxin oxidoreductaseClostridium acetobutylicum ATCC 824

Compounds (13)

CompoundDescription
hydronium ion
Thiamine PyrophosphateThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
NADH
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
hexanoyl-coenzyme A
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
n-hexanal
1-hexanolRN given refers to parent cpd
Coenzyme A
acetoacetyl CoA
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.