Page last updated: 2024-10-06

pyruvate dehydrogenase complex

Proteins (4)

ProteinSynonymsTaxonomy
Dihydrolipoyl dehydrogenase, mitochondrialEC 1.8.1.4; Dihydrolipoamide dehydrogenase; Glycine decarboxylase complex subunit L; Lipoamide dehydrogenase component of pyruvate dehydrogenase complex; Pyruvate dehydrogenase complex E3 componentSaccharomyces cerevisiae S288C
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialEC 2.3.1.12; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Pyruvate dehydrogenase complex component E2; PDC-E2; PDCE2Saccharomyces cerevisiae S288C
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrialEC 1.2.4.1; Pyruvate dehydrogenase complex component E1 alpha; PDHE1-ASaccharomyces cerevisiae S288C
Pyruvate dehydrogenase E1 component subunit beta, mitochondrialEC 1.2.4.1; Pyruvate dehydrogenase complex component E1 beta; PDHE1-BSaccharomyces cerevisiae S288C

Compounds (7)

CompoundDescription
hydronium ion
NADH
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.