Page last updated: 2024-10-06

pyrimidine deoxyribonucleotides de novo biosynthesis III

Proteins (11)

ProteinSynonymsTaxonomy
Flavin-dependent thymidylate synthaseFDTS; EC 2.1.1.148; FAD-dependent thymidylate synthase; Thymidylate synthase ThyX; TS; TSaseMycobacterium tuberculosis H37Rv
Thymidylate kinaseEC 2.7.4.9; Thymidine monophosphate kinase; dTMP kinase; TMPKMycobacterium tuberculosis H37Rv
Ribonucleoside-diphosphate reductase subunit alphaEC 1.17.4.1; Ribonucleotide reductaseChlamydia trachomatis D/UW-3/CX
Ribonucleoside-diphosphate reductase subunit betaEC 1.17.4.1; Ribonucleotide reductase small subunitChlamydia trachomatis D/UW-3/CX
Flavin-dependent thymidylate synthaseFDTS; EC 2.1.1.148; FAD-dependent thymidylate synthase; Thymidylate synthase ThyX; TS; TSaseHelicobacter pylori 26695
Flavin-dependent thymidylate synthaseFDTS; EC 2.1.1.148; FAD-dependent thymidylate synthase; Thymidylate synthase ThyX; TS; TSaseThermotoga maritima MSB8
Nucleoside-triphosphatase THEP1NTPase THEP1; EC 3.6.1.15; Nucleoside triphosphate phosphohydrolaseAquifex aeolicus VF5
UPF0159 protein CT_632Chlamydia trachomatis D/UW-3/CX
Nucleoside diphosphate kinaseNDK; NDP kinase; EC 2.7.4.6; Nucleoside-2-P kinaseHalobacterium salinarum NRC-1
dUTPase Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
Vitamin B12-dependent ribonucleotide reductase Thermotoga maritima

Compounds (26)

CompoundDescription
diphosphoric acid
hydronium ion
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
hydroxyureaAn antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
Orthophosphate
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
cobamamide
thymidine 5'-triphosphateRN given refers to parent cpd
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
Thymidine Monophosphate5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
dithiothreitolA reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Cytidine TriphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
2'-deoxyuridylic acidRN given refers to parent cpd
Cytidine DiphosphateCytidine 5'-(trihydrogen diphosphate). A cytosine nucleotide containing two phosphate groups esterified to the sugar moiety. Synonyms: CRPP; cytidine pyrophosphate.
Deoxycytidine MonophosphateDeoxycytidine (dihydrogen phosphate). A deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the 2'-,3'- or 5- positions.
thymidine 5'-diphosphatesee also record for thymidine 3',5'-diphosphate, RN 2863-04-9
deoxyuridine triphosphate
2'-deoxycytidine 5'-triphosphateRN given refers to unlabeled parent cpd
deoxyuridine triphosphate
deoxyadenosine diphosphateRN given refers to parent cpd.
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)