| Protein | Synonyms | Taxonomy |
|---|
| Inosine-5'-monophosphate dehydrogenase 2 | IMP dehydrogenase 2; IMPD 2; IMPDH 2; EC 1.1.1.205; IMPDH-II | Homo sapiens (human) |
| Xanthine dehydrogenase/oxidase | | Homo sapiens (human) |
| Cytosolic purine 5'-nucleotidase | EC 3.1.3.5; Cytosolic 5'-nucleotidase II | Homo sapiens (human) |
| Inosine-5'-monophosphate dehydrogenase 1 | IMP dehydrogenase 1; IMPD 1; IMPDH 1; EC 1.1.1.205; IMPDH-I | Homo sapiens (human) |
| Guanine deaminase | Guanase; Guanine aminase; EC 3.5.4.3; Guanine aminohydrolase; GAH; p51-nedasin | Homo sapiens (human) |
| Purine nucleoside phosphorylase | PNP; EC 2.4.2.1; Inosine phosphorylase; Inosine-guanosine phosphorylase | Homo sapiens (human) |
| Adenosine deaminase | EC 3.5.4.4; Adenosine aminohydrolase | Homo sapiens (human) |
| 5'-nucleotidase | 5'-NT; EC 3.1.3.5; Ecto-5'-nucleotidase | Homo sapiens (human) |
| Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | | Rattus norvegicus (Norway rat) |
| Inosine-5'-monophosphate dehydrogenase | IMP dehydrogenase; IMPD; IMPDH; EC 1.1.1.205 | Escherichia coli K-12 |
| Purine nucleoside phosphorylase DeoD-type | PNP; EC 2.4.2.1 | Escherichia coli K-12 |
| Pyrimidine/purine nucleoside phosphorylase | EC 2.4.2.1; EC 2.4.2.2; Adenosine phosphorylase; Cytidine phosphorylase; Guanosine phosphorylase; 2.4.2.15; Inosine phosphorylase; Thymidine phosphorylase; 2.4.2.4; Uridine phosphorylase; 2.4.2.3; Xanthosine phosphorylase | Escherichia coli K-12 |
| Adenosine deaminase | EC 3.5.4.4; Adenosine aminohydrolase | Escherichia coli K-12 |
| Alkaline phosphatase | APase; EC 3.1.3.1 | Escherichia coli K-12 |
| Purine nucleoside phosphorylase 2 | EC 2.4.2.1; Inosine-guanosine phosphorylase; Purine nucleoside phosphorylase II; PNP II; Xanthosine phosphorylase | Escherichia coli K-12 |
| Guanine deaminase | Guanase; Guanine aminase; EC 3.5.4.3; Guanine aminohydrolase; GAH | Escherichia coli K-12 |
| GMP/IMP nucleotidase YrfG | EC 3.1.3.5 | Escherichia coli K-12 |
| Xanthine dehydrogenase/oxidase | | Mus musculus (house mouse) |
| Putative xanthine dehydrogenase molybdenum-binding subunit XdhA | EC 1.17.1.4 | Escherichia coli K-12 |
| Putative xanthine dehydrogenase FAD-binding subunit XdhB | EC 1.17.1.4 | Escherichia coli K-12 |
| Putative xanthine dehydrogenase iron-sulfur-binding subunit XdhC | | Escherichia coli K-12 |
| Cytosolic 5'-nucleotidase 1A | cN1A; EC 3.1.3.5; Cytosolic 5'-nucleotidase IA; cN-I; cN-IA | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| Cesium | A member of the alkali metals. It has an atomic symbol Cs, atomic number 50, and atomic weight 132.91. Cesium has many industrial applications, including the construction of atomic clocks based on its atomic vibrational frequency. |
| Rubidium | An element that is an alkali metal. It has an atomic symbol Rb, atomic number 37, and atomic weight 85.47. It is used as a chemical reagent and in the manufacture of photoelectric cells. |
| NADH | |
| Ammonium | |
| Manganese | A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035) |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| adenosine | A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| potassium | An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| 9-(2-hydroxy-3-nonyl)adenine | specific inhibitor of adenosine deaminase |
| 1,10-phenanthroline | RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| xanthosine | |
| xanthine | A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed) |
| xanthosine monophosphate | |
| ribose 1-phosphate, (alpha-D)-isomer | |
| Coformycin | A ribonucleoside antibiotic synergist and adenosine deaminase inhibitor isolated from Nocardia interforma and Streptomyces kaniharaensis. It is proposed as an antineoplastic synergist and immunosuppressant. |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |
| mizoribine 5'-monophosphate | |