Page last updated: 2024-10-06

photosynthetic 3-hydroxybutanoate biosynthesis (engineered)

Proteins (63)

ProteinSynonymsTaxonomy
Fructose-bisphosphate aldolase class 2FBP aldolase; FBPA; EC 4.1.2.13; Fructose-1,6-bisphosphate aldolase; Fructose-bisphosphate aldolase class IIEscherichia coli K-12
Acetoacetyl-CoA reductaseCupriavidus necator
Photosystem II protein D1 1PSII D1 protein 1; EC 1.10.3.9; Photosystem II Q(B) protein 1Synechocystis sp. PCC 6803 substr. Kazusa
Photosystem II D2 proteinPSII D2 protein; EC 1.10.3.9; Photosystem Q(A) proteinSynechocystis sp. PCC 6803 substr. Kazusa
Fructose-bisphosphate aldolase class 1EC 4.1.2.13; Fructose-bisphosphate aldolase class I; FBP aldolaseEscherichia coli K-12
Pyruvate kinase IEC 2.7.1.40; PK-1Escherichia coli K-12
Pyruvate kinase IIEC 2.7.1.40; PK-2Escherichia coli K-12
Photosystem I P700 chlorophyll a apoprotein A2EC 1.97.1.12; PsaBSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem I iron-sulfur centerEC 1.97.1.12; 9 kDa polypeptide; PSI-C; Photosystem I subunit VII; PsaCSynechocystis sp. PCC 6803 substr. Kazusa
3-hydroxybutyryl-CoA dehydrogenaseEC 1.1.1.157; Beta-hydroxybutyryl-CoA dehydrogenase; BHBDClostridium acetobutylicum ATCC 824
Alkaline phosphataseAPase; EC 3.1.3.1Escherichia coli K-12
Ribose-5-phosphate isomerase AEC 5.3.1.6; Phosphoriboisomerase A; PRIEscherichia coli K-12
Ribose-5-phosphate isomerase BEC 5.3.1.6; Phosphoriboisomerase BEscherichia coli K-12
Phosphocarrier protein HPrHistidine-containing proteinEscherichia coli K-12
Triosephosphate isomeraseTIM; TPI; EC 5.3.1.1; Triose-phosphate isomeraseEscherichia coli K-12
EnolaseEC 4.2.1.11; 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydrataseEscherichia coli K-12
Dihydrolipoyl dehydrogenaseEC 1.8.1.4; Dihydrolipoamide dehydrogenase; E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes; Glycine cleavage system L proteinEscherichia coli K-12
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complexEC 2.3.1.12; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; E2Escherichia coli K-12
Photosystem I P700 chlorophyll a apoprotein A1EC 1.97.1.12; PsaASynechocystis sp. PCC 6803 substr. Kazusa
Pyruvate dehydrogenase E1 componentPDH E1 component; EC 1.2.4.1Escherichia coli K-12
Acyl-CoA thioesterase 2EC 3.1.2.20; Thioesterase II; TEIIEscherichia coli K-12
Acetyl-CoA acetyltransferaseEC 2.3.1.9; Acetoacetyl-CoA thiolase; Beta-ketothiolaseCupriavidus necator H16
Acetyl-CoA acetyltransferaseEC 2.3.1.9; Acetoacetyl-CoA thiolaseClostridium acetobutylicum ATCC 824
Acetyl-CoA acetyltransferaseEC 2.3.1.9; Acetoacetyl-CoA thiolaseEscherichia coli K-12
Beta-ketothiolase BktBEC 2.3.1.16; EC 2.3.1.9; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferaseCupriavidus necator H16
Photosystem II manganese-stabilizing polypeptideMSPSynechocystis sp. PCC 6803 substr. Kazusa
Cytochrome c-550Cytochrome c549; Cytochrome c550; Low-potential cytochrome cSynechocystis sp. PCC 6803 substr. Kazusa
2,3-bisphosphoglycerate-independent phosphoglycerate mutaseBPG-independent PGAM; Phosphoglyceromutase; iPGM; EC 5.4.2.12Escherichia coli K-12
Fructose-1,6-bisphosphatase class 1FBPase class 1; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1Escherichia coli K-12
Fructose-1,6-bisphosphatase class 1FBPase class 1; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1Synechocystis sp. PCC 6803 substr. Kazusa
Protein PsbNSynechocystis sp. PCC 6803 substr. Kazusa
Phosphoglycerate kinaseEC 2.7.2.3Escherichia coli K-12
Fructose-1,6-bisphosphatase 1 class 2FBPase 1 class 2; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1 class 2Escherichia coli K-12
Ribulose-phosphate 3-epimeraseEC 5.1.3.1; Pentose-5-phosphate 3-epimerase; PPE; R5P3EEscherichia coli K-12
Fructose-1,6-bisphosphatase 2 class 2FBPase 2 class 2; EC 3.1.3.11; D-fructose-1,6-bisphosphate 1-phosphohydrolase 2 class 2Escherichia coli K-12
Pyridoxal phosphate phosphatase YbhAPLP phosphatase; EC 3.1.3.74Escherichia coli K-12
Transketolase 1TK 1; EC 2.2.1.1Escherichia coli K-12
Transketolase 2TK 2; EC 2.2.1.1Escherichia coli K-12
Ribulose bisphosphate carboxylase large chainRuBisCO large subunit; EC 4.1.1.39Synechocystis sp. PCC 6803 substr. Kazusa
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphataseFBPase class 2/SBPase; EC 3.1.3.11; EC 3.1.3.37Synechocystis sp. PCC 6803 substr. Kazusa
Ssr0332 proteinSynechocystis sp. PCC 6803 substr. Kazusa
Ribulose bisphosphate carboxylase small chainRuBisCO small subunit; EC 4.1.1.39Synechocystis sp. PCC 6803 substr. Kazusa
Major histocompatibility complex antigen H-2Kbm29 Mus musculus (house mouse)
Photosystem II CP47 reaction center proteinPSII 47 kDa protein; Protein CP-47Synechocystis sp. PCC 6803 substr. Kazusa
Photosystem II CP43 reaction center proteinPSII 43 kDa protein; Protein CP-43Synechocystis sp. PCC 6803 substr. Kazusa
Photosystem I reaction center subunit IVPhotosystem I 8.1 kDa protein; p30 proteinSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem II reaction center protein HPSII-H; 6 kDa phosphoproteinSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem II reaction center protein KPSII-KSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem I reaction center subunit IIPhotosystem I 16 kDa polypeptide; PSI-DSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem I reaction center subunit IIIPSI-FSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem I reaction center subunit XIPSI subunit V; PSI-LSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem II reaction center X proteinSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem II reaction center protein MPSII-MSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem I reaction center subunit PsaK 1Photosystem I subunit X 1Synechocystis sp. PCC 6803 substr. Kazusa
Photosystem I reaction center subunit XIIPSI-MSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem II reaction center protein JPSII-JSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem I reaction center subunit PsaK 2Photosystem I subunit X 2Synechocystis sp. PCC 6803 substr. Kazusa
Photosystem II reaction center protein IPSII-I; PSII 4.4 kDa proteinSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem I reaction center subunit IXSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem I reaction center subunit VIIISynechocystis sp. PCC 6803 substr. Kazusa
Photosystem II 12 kDa extrinsic proteinPS II complex 12 kDa extrinsic protein; PSII-USynechocystis sp. PCC 6803 substr. Kazusa
Photosystem II reaction center protein LPSII-LSynechocystis sp. PCC 6803 substr. Kazusa
Photosystem II reaction center Psb28 proteinPhotosystem II 13 kDa protein; Photosystem II reaction center W proteinSynechocystis sp. PCC 6803 substr. Kazusa

Compounds (49)

CompoundDescription
hydronium ion
Thiamine PyrophosphateThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
NADH
Ammonium
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
fluoridesInorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices.
LithiumAn element in the alkali metals family. It has the atomic symbol Li, atomic number 3, and atomic weight [6.938; 6.997]. Salts of lithium are used in treating BIPOLAR DISORDER.
serum p-componentclose relation to C reactive protein; may be ovosomucoid
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
potassium chlorideA white crystal or crystalline powder used in BUFFERS; FERTILIZERS; and EXPLOSIVES. It can be used to replenish ELECTROLYTES and restore WATER-ELECTROLYTE BALANCE in treating HYPOKALEMIA.
SuperoxidesHighly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
NickelA trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
succinyl-coenzyme A
iodoacetamideAn alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate.
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
2-ketobutyrate
glyoxylate
dithiothreitolA reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols.
Edetic AcidA chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.
xylulose-5-phosphateRN given refers to cpd with unspecified isomeric designation
fructose-1,6-diphosphateRN refers to (D)-isomer
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
bromopyruvate
tellurate
arabinose 5-phosphateRN given refers to (D)-isomer
ticrynafenA novel diuretic with uricosuric action. It has been proposed as an antihypertensive agent.
Coenzyme A
sapropterinRN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
acetoacetyl CoA
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
sedoheptulose 7-phosphate
glycerate 1,3-biphosphate
sedoheptulose 1,7-bisphosphate
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
thiamine thiothiazolone pyrophosphatethiamin pyrophosphate with its thiazole ring altered to thiothiazolone
2'-methoxythiamine pyrophosphatestructure in first source