Page last updated: 2024-10-06

phosphinothricin tripeptide biosynthesis

Proteins (19)

ProteinSynonymsTaxonomy
Phosphinothricin N-acetyltransferasePPT N-acetyltransferase; EC 2.3.1.183; Phosphinothricin-resistance protein
Phosphonopyruvate decarboxylaseEC 4.1.1.82
Carboxyvinyl-carboxyphosphonate phosphorylmutaseEC 2.7.8.23; Carboxyphosphonoenolpyruvate phosphonomutase; CPEP phosphonomutaseStreptomyces hygroscopicus
Peptide synthetase PhsCStreptomyces viridochromogenes
Phosphonoacetaldehyde reductaseEC 1.1.1.309
Acetyl-hydrolaseEC 3.1.1.-Streptomyces hygroscopicus
PhpFStreptomyces viridochromogenes
2-hydroxyethylphosphonate dioxygenaseEC 1.13.11.72; Hydroxyethylphosphonate dioxygenase; Phosphinothricin tripeptide biosynthesis protein D
2-phosphinomethylmalate synthasePMS; EC 2.3.3.18; PMM synthaseStreptomyces hygroscopicus
Phosphopyruvate hydratase Streptomyces viridochromogenes
Aconitate hydratase Streptomyces viridochromogenes
PhpJ Streptomyces viridochromogenes
Putative PhpM Streptomyces viridochromogenes
Phosphoenolpyruvate phosphomutaseStreptomyces viridochromogenes
Peptide synthetase PhsAStreptomyces viridochromogenes
PhpE Streptomyces viridochromogenes
BcpD Streptomyces hygroscopicus
PhpGStreptomyces viridochromogenes
Putative PhpLStreptomyces viridochromogenes

Compounds (31)

CompoundDescription
diphosphoric acid
hydronium ion
CobaltA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
NADH
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
Orthophosphate
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
iodoacetamideAn alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
formate
5'-deoxyadenosinemain heading DEOXYADENOSINE refers to the 3' cpd
Edetic AcidA chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Cytidine TriphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
hydroxymethylphosphonate
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Coenzyme A
phosphonoacetaldehyde
2-hydroxyethyl phosphonate
3-phosphonopyruvate
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
Phosphonoformate