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phosphatidylcholine biosynthesis I

Proteins (8)

ProteinSynonymsTaxonomy
Choline/ethanolaminephosphotransferase 1hCEPT1; EC 2.7.8.1; EC 2.7.8.2Homo sapiens (human)
Choline kinase alphaCK; EC 2.7.1.32; CHETK-alpha; Ethanolamine kinase; EK; 2.7.1.82Homo sapiens (human)
Choline-phosphate cytidylyltransferase AEC 2.7.7.15; CCT-alpha; CTP:phosphocholine cytidylyltransferase A; CCT A; CT A; Phosphorylcholine transferase AHomo sapiens (human)
Choline kinaseEC 2.7.1.32Saccharomyces cerevisiae S288C
Cholinephosphotransferase 1EC 2.7.8.2; Aminoalcohol phosphotransferase CPT1; Diacylglycerol cholinephosphotransferase 1; Sn-1,2-diacylglycerol cholinephosphotransferase; CHOPTSaccharomyces cerevisiae S288C
Choline-phosphate cytidylyltransferaseEC 2.7.7.15; CTP:phosphocholine cytidylyltransferase; CCT; CT; Phosphorylcholine transferaseSaccharomyces cerevisiae S288C
CDP-alcohol phosphatidyltransferase family proteinTreponema denticola ATCC 35405
CTP:phosphocholine cytidylyltransferase/choline kinaseTreponema denticola

Compounds (15)

CompoundDescription
diphosphoric acid
hydronium ion
cytidine diphosphate cholineDonor of choline in biosynthesis of choline-containing phosphoglycerides.
MercuryA silver metallic element that exists as a liquid at room temperature. It has the atomic symbol Hg (from hydrargyrum, liquid silver), atomic number 80, and atomic weight 200.59. Mercury is used in many industrial applications and its salts have been employed therapeutically as purgatives, antisyphilitics, disinfectants, and astringents. It can be absorbed through the skin and mucous membranes which leads to MERCURY POISONING. Because of its toxicity, the clinical use of mercury and mercurials is diminishing.
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
cholineA basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
PhosphorylcholineCalcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
MagnesiumA metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION.
hemicholinium 3A potent inhibitor of the high affinity uptake system for CHOLINE. It has less effect on the low affinity uptake system. Since choline is one of the components of ACETYLCHOLINE, treatment with hemicholinium can deplete acetylcholine from cholinergic terminals. Hemicholinium 3 is commonly used as a research tool in animal and in vitro experiments.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
octyl glucoside
Cytidine MonophosphateCytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Cytidine TriphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.