| Protein | Synonyms | Taxonomy |
|---|
| Phospho-N-acetylmuramoyl-pentapeptide-transferase | EC 2.7.8.13; UDP-MurNAc-pentapeptide phosphotransferase | Staphylococcus aureus |
| Penicillin-binding protein 4 | | Staphylococcus aureus |
| Cell division protein FtsI | | Staphylococcus aureus |
| MecA | | Staphylococcus aureus |
| UDP-N-acetylmuramate--L-alanine ligase | EC 6.3.2.8; UDP-N-acetylmuramoyl-L-alanine synthetase | Staphylococcus aureus |
| UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 | EC 2.5.1.7; Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1 | Staphylococcus aureus subsp. aureus N315 |
| Cell division protein FtsI [Peptidoglycan synthetase] / Transpeptidase, Penicillin binding protein transpeptidase domain, Penicillin-binding protein 3 | | Staphylococcus aureus |
| Monofunctional glycosyltransferase | MGT; EC 2.4.1.129; Peptidoglycan TGase | Staphylococcus aureus subsp. aureus NCTC 8325 |
| Glutamate racemase | EC 5.1.1.3 | Staphylococcus haemolyticus |
| UDP-N-acetylmuramoylalanine--D-glutamate ligase | EC 6.3.2.9; D-glutamic acid-adding enzyme; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase | Staphylococcus aureus |
| UDP-N-acetylenolpyruvoylglucosamine reductase | EC 1.3.1.98; UDP-N-acetylmuramate dehydrogenase | Staphylococcus aureus |
| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | | Staphylococcus aureus subsp. aureus NCTC 8325 |
| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | EC 6.3.2.7; L-lysine-adding enzyme; UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase; UDP-MurNAc-tripeptide synthetase; UDP-N-acetylmuramyl-tripeptide synthetase | Staphylococcus aureus subsp. aureus COL |
| Aminoacyltransferase FemA | EC 2.3.2.17; Factor essential for expression of methicillin resistance A; N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-glycyl)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase | Staphylococcus aureus |
| Aminoacyltransferase FemB | EC 2.3.2.18; Factor essential for expression of methicillin resistance B; N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase | Staphylococcus aureus |
| UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 | EC 2.5.1.7; Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 | Staphylococcus aureus subsp. aureus N315 |
| UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | EC 2.4.1.227; Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase | Staphylococcus aureus subsp. aureus COL |
| Lipid II:glycine glycyltransferase | EC 2.3.2.16; Factor essential for expression of methicillin resistance X | Staphylococcus aureus subsp. aureus Mu50 |
| D-alanine--D-alanine ligase | EC 6.3.2.4; D-Ala-D-Ala ligase; D-alanylalanine synthetase | Staphylococcus aureus subsp. aureus COL |
| DD-transpeptidase | | Staphylococcus aureus |
| Compound | Description |
|---|
| hydronium ion | |
| Cobalt | A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. |
| uridine diphosphate | A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. |
| Ammonium | |
| Methicillin | One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection. |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| Manganese | A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035) |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| D-Glutamate | |
| glutamate | |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| Cycloserine | Antibiotic substance produced by Streptomyces garyphalus. |
| Uridine Monophosphate | 5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position. |
| uridine diphosphate n-acetylmuramic acid | A nucleoside diphosphate sugar which is formed from UDP-N-acetylglucosamine and phosphoenolpyruvate. It serves as the building block upon which peptidoglycan is formed. |
| lipid II | |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |