papaverine biosynthesis

Proteins (3)

Protein	Synonyms	Taxonomy
3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase 1	4'-OMT1; Ps4'OMT1; EC 2.1.1.116; S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase	Papaver somniferum (opium poppy)
Norreticuline-7-O-methyltransferase	EC 2.1.1.-	Papaver somniferum (opium poppy)
FAD-dependent oxidoreductase		Papaver somniferum (opium poppy)

Compound	Description
hydronium ion
papaverine	An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Water	A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
s-adenosylmethionine	Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
laudanosine	opium alkaloid