Page last updated: 2024-10-06
oleandomycin biosynthesis
Proteins (7)
| Protein | Synonyms | Taxonomy |
|---|
| L-olivosyl-oleandolide 3-O-methyltransferase | EC 2.1.1.239; Oleandomycin biosynthesis protein Y | Streptomyces antibioticus |
| Glycosyltransferase | | Streptomyces antibioticus |
| Glycosyltransferase | | Streptomyces antibioticus |
| Cytochrome P-450 | | Streptomyces antibioticus |
| 8,8a-deoxyoleandolide synthase 1 | | Streptomyces antibioticus |
| Oleandomycin polyketide synthase, modules 5 and 6 | | Streptomyces antibioticus |
| 8,8a-deoxyoleandolide synthase 2 | | Streptomyces antibioticus |
Compounds (14)
| Compound | Description |
|---|
| hydronium ion | |
| Cobalt | A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. |
| Oleandomycin Phosphate | |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| 8,8a-deoxyoleandolide | 14-membered deoxy aglycone lactone of oleandomycin; structure |
| oleandolide | structure given in first source; shows no antibacterial activity |
| thymidine 5'-diphosphate | see also record for thymidine 3',5'-diphosphate, RN 2863-04-9 |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| Coenzyme A | |
| Acetyl Coenzyme A | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |