Page last updated: 2024-10-06

narbomycin, pikromycin and novapikromycin biosynthesis

Proteins (7)

ProteinSynonymsTaxonomy
Narbonolide/10-deoxymethynolide synthase PikA4, module 6EC 2.3.1.239; EC 2.3.1.240; Narbonolide/10-deoxymethynolide synthase PikAIV; Pikromycin polyketide synthase component PikAIV; Pikromycin PKS component PikAIV; Type I modular polyketide synthase PikAIV; PKSStreptomyces venezuelae
Narbonolide/10-deoxymethynolide synthase PikA3, module 5EC 2.3.1.239; EC 2.3.1.240; Narbonolide/10-deoxymethynolide synthase PikAIII; Pikromycin polyketide synthase component PikAIII; Pikromycin PKS component PikAIII; Type I modular polyketide synthase PikAIII; PKSStreptomyces venezuelae
Narbonolide/10-deoxymethynolide synthase PikA2, modules 3 and 4EC 2.3.1.239; EC 2.3.1.240; Narbonolide/10-deoxymethynolide synthase PikAII; Pikromycin polyketide synthase component PikAII; Pikromycin PKS component PikAII; Type I modular polyketide synthase PikAII; PKSStreptomyces venezuelae
Narbonolide/10-deoxymethynolide synthase PikA1, modules 1 and 2EC 2.3.1.239; EC 2.3.1.240; Narbonolide/10-deoxymethynolide synthase PikAI; Pikromycin polyketide synthase component PikAI; Pikromycin PKS component PikAI; Type I modular polyketide synthase PikAI; PKSStreptomyces venezuelae
Thioesterase PikA5EC 3.1.2.-; Editing thioesterase; Thioesterase II; TEII; Type II thioesteraseStreptomyces venezuelae
Cytochrome P450 monooxygenase PikCEC 1.14.15.33; Cytochrome P450 monooxygenase PicK; Narbomycin C-12 hydroxylase; Pikromycin synthase CYP107L1Streptomyces venezuelae
10-deoxymethynolide desosaminyltransferaseEC 2.4.1.277Streptomyces venezuelae

Compounds (14)

CompoundDescription
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
narbomycinstructure
picromycinstructure
novapikromycinfrom the pikromycin biosynthetic pathway of Streptomyces venezuelae; structure in first source
neopikromycinfrom the pikromycin biosynthetic pathway of Streptomyces venezuelae; structure in first source
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
narbonolidestructure in first source
thymidine 5'-diphosphatesee also record for thymidine 3',5'-diphosphate, RN 2863-04-9
Coenzyme A
Malonyl Coenzyme AA coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.