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meta cleavage pathway of aromatic compounds

Proteins (14)

ProteinSynonymsTaxonomy
MetapyrocatechaseMPC; EC 1.13.11.2; CatO2ase; Catechol 2,3-dioxygenasePseudomonas putida
4-hydroxy-2-oxovalerate aldolaseHOA; EC 4.1.3.39; 4-hydroxy-2-keto-pentanoic acid aldolase; 4-hydroxy-2-oxopentanoate aldolasePseudomonas sp. CF600
4-hydroxy-2-oxovalerate aldolase 1HOA 1; EC 4.1.3.39; 4-hydroxy-2-keto-pentanoic acid aldolase 1; 4-hydroxy-2-oxopentanoate aldolase 1Pseudomonas putida F1
2-hydroxymuconic semialdehyde dehydrogenaseHMSD; EC 1.2.1.85Pseudomonas putida
4-oxalocrotonate decarboxylase4-OD; EC 4.1.1.77Pseudomonas putida
Acetaldehyde dehydrogenaseEC 1.2.1.10; Acetaldehyde dehydrogenase [acetylating]Pseudomonas sp. CF600
2-hydroxymuconate tautomeraseEC 5.3.2.6; 4-oxalocrotonate tautomerase; 4-OTPseudomonas putida
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenaseEC 1.3.1.25; 2-hydro-1,2-dihydroxybenzoate dehydrogenase; DHB dehydrogenase; Cis-1,2-dihydroxy-3,4-cyclohexadiene-1-carboxylate dehydrogenase; Cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenasePseudomonas putida
Toluate 1,2-dioxygenase subunit alphaEC 1.14.12.-Pseudomonas putida
Toluate 1,2-dioxygenase subunit betaEC 1.14.12.-Pseudomonas putida
Toluate 1,2-dioxygenase electron transfer componentPseudomonas putida
2-hydroxypent-2,4-dienoate hydrataseHPH; EC 4.2.-.-; 2-oxopent-4-enoate hydratasePseudomonas putida
Acetaldehyde dehydrogenase Pseudomonas putida
2-hydroxymuconate semialdehyde hydrolaseHMSH; EC 3.7.1.9; 2-hydroxymuconic semialdehyde hydrolasePseudomonas putida

Compounds (16)

CompoundDescription
hydronium ion
NADH
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
acetaldehydeA colorless, flammable liquid used in the manufacture of acetic acid, perfumes, and flavors. It is also an intermediate in the metabolism of alcohol. It has a general narcotic action and also causes irritation of mucous membranes. Large doses may cause death from respiratory paralysis.
Benzoate
formate
catecholRN given refers to unlabeled parent cpd
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.