Page last updated: 2024-10-06

isopropanol biosynthesis (engineered)

Proteins (5)

ProteinSynonymsTaxonomy
Acetoacetate decarboxylaseAAD; ADC; EC 4.1.1.4Clostridium acetobutylicum ATCC 824
Acetyl-CoA acetyltransferaseEC 2.3.1.9; Acetoacetyl-CoA thiolaseClostridium acetobutylicum ATCC 824
Butyrate--acetoacetate CoA-transferase subunit BCoat B; EC 2.8.3.9; Acetoacetyl-CoA:acetate/butyrate CoA-transferase subunit BClostridium acetobutylicum ATCC 824
Butyrate--acetoacetate CoA-transferase subunit ACoat A; EC 2.8.3.9; Acetoacetyl-CoA:acetate/butyrate:CoA transferase subunit AClostridium acetobutylicum ATCC 824
Pyruvate:ferredoxin oxidoreductaseClostridium acetobutylicum ATCC 824

Compounds (22)

CompoundDescription
hydronium ion
Thiamine PyrophosphateThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
2-propanolAn isomer of 1-PROPANOL. It is a colorless liquid having disinfectant properties. It is used in the manufacture of acetone and its derivatives and as a solvent. Topically, it is used as an antiseptic.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
iodoacetamideAn alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate.
benzoylacetone
Pyruvic AcidAn intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
acetoneA colorless liquid used as a solvent and an antiseptic. It is one of the ketone bodies produced during ketoacidosis.
Sodium Dodecyl SulfateAn anionic surfactant, usually a mixture of sodium alkyl sulfates, mainly the lauryl; lowers surface tension of aqueous solutions; used as fat emulsifier, wetting agent, detergent in cosmetics, pharmaceuticals and toothpastes; also as research tool in protein biochemistry.
acetopyruvate
4-ChloromercuribenzenesulfonateA cytotoxic sulfhydryl reagent that inhibits several subcellular metabolic systems and is used as a tool in cellular physiology.
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
acetoacetate
hydrogen cyanideHydrogen cyanide (HCN); A toxic liquid or colorless gas. It is found in the smoke of various tobacco products and released by combustion of nitrogen-containing organic materials.
Coenzyme A
sapropterinRN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases
acetylacetone
acetoacetyl CoA
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.