Page last updated: 2024-10-06
indolmycin biosynthesis
Proteins (8)
| Protein | Synonyms | Taxonomy |
|---|
| Indolepyruvate C-methyltransferase | EC 2.1.1.47; S-adenosylmethionine: indolepyruvate 3-methyltransferase | Streptomyces griseus |
| N-demethylindolmycin N-methyltransferase | EC 2.1.1.328 | Streptomyces griseus |
| Ind5 | | |
| Ind3 | | |
| Histidinol-phosphate aminotransferase | | Streptomyces griseus |
| Ind4 | | |
| Ind6 | | |
| Beta-methylindole-3-pyruvate reductase | EC 1.1.1.397; Beta-methylindolepyruvate dehydrogenase | Streptomyces griseus |
Compounds (17)
| Compound | Description |
|---|
| diphosphoric acid | |
| hydronium ion | |
| Arginine | An essential amino acid that is physiologically active in the L-form. |
| NADH | |
| Ammonium | |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| TAK083 | structure in first source |
| Pyruvic Acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| delta-1-pyrroline-5-carboxylate | (L)-isomer is the biologically active form; RN given refers to cpd without isomeric designation; structure |
| 1,10-phenanthroline | RN given refers to parent cpd; inhibits Zn-dependent metalloproteinases |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| ethylmaleimide | A sulfhydryl reagent that is widely used in experimental biochemical studies. |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| 2,2'-dipyridyl | A reagent used for the determination of iron. |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |