Pathways > glutathione-mediated detoxification I
Page last updated: 2024-10-06
glutathione-mediated detoxification I
Proteins (10)
| Protein | Synonyms | Taxonomy |
|---|
| Multidrug resistance-associated protein 1 | EC 7.6.2.2; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; 7.6.2.3; Leukotriene C(4) transporter; LTC4 transporter | Homo sapiens (human) |
| Maleylacetoacetate isomerase | MAAI; EC 5.2.1.2; GSTZ1-1; Glutathione S-transferase zeta 1; 2.5.1.18 | Homo sapiens (human) |
| Aminopeptidase N | AP-N; rAPN; EC 3.4.11.2; Alanyl aminopeptidase; Aminopeptidase M; AP-M; Kidney Zn peptidase; KZP; Microsomal aminopeptidase | Rattus norvegicus (Norway rat) |
| Glutathione S-transferase A2 | EC 2.5.1.18; GST HA subunit 2; GST class-alpha member 2; GST-gamma; GSTA2-2; GTH2 | Homo sapiens (human) |
| Glutathione S-transferase A1 | EC 2.5.1.18; 13-hydroperoxyoctadecadienoate peroxidase; 1.11.1.-; Androst-5-ene-3,17-dione isomerase; 5.3.3.-; GST HA subunit 1; GST class-alpha member 1; GST-epsilon; GSTA1-1; GTH1 | Homo sapiens (human) |
| Cytosol aminopeptidase | EC 3.4.11.1; Cysteinylglycine-S-conjugate dipeptidase; 3.4.13.23; Leucine aminopeptidase 3; LAP-3; Leucyl aminopeptidase; LAP; Peptidase S; Proline aminopeptidase; 3.4.11.5; Prolyl aminopeptidase | Rattus norvegicus (Norway rat) |
| Glutathione hydrolase 5 proenzyme | EC 3.4.19.13; Gamma-glutamyl transpeptidase-related enzyme; GGT-rel; Gamma-glutamyltransferase 5; GGT 5; 2.3.2.2; Gamma-glutamyltransferase-like activity 1; Gamma-glutamyltranspeptidase 5; Leukotriene-C4 hydrolase; 3.4.19.14 | Homo sapiens (human) |
| N-acetyltransferase 8 | EC 2.3.1.-; Acetyltransferase 2; ATase2; Camello-like protein 4; Cysteinyl-conjugate N-acetyltransferase; CCNAT; 2.3.1.80 | Rattus norvegicus (Norway rat) |
| N-acetyltransferase 8 | EC 2.3.1.-; Acetyltransferase 2; ATase2; Camello-like protein 1; Cysteinyl-conjugate N-acetyltransferase; CCNAT; 2.3.1.80 | Homo sapiens (human) |
| N-acetyltransferase domain-containing protein | | Sus scrofa (pig) |
Compounds (12)
| Compound | Description |
|---|
| hydronium ion | |
| Ammonium | |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Pyruvic Acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| ethylmaleimide | A sulfhydryl reagent that is widely used in experimental biochemical studies. |
| glutamate | |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| Coenzyme A | |
| Acetyl Coenzyme A | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |