| Protein | Synonyms | Taxonomy |
|---|
| Dipeptidase gliJ | EC 3.4.13.19; Gliotoxin biosynthesis protein J | Aspergillus fumigatus Af293 |
| Nonribosomal peptide synthetase gliP | NRPS gliP; EC 6.3.2.-; Gliotoxin biosynthesis protein P | Aspergillus fumigatus Af293 |
| Gamma-glutamyl cyclotransferase gliK | GGCT gliK; EC 4.3.2.9; Gliotoxin biosynthesis protein K | Aspergillus fumigatus Af293 |
| Glutathione S-transferase gliG | EC 2.5.1.18; Gliotoxin biosynthesis protein G | Aspergillus fumigatus Af293 |
| Thioredoxin reductase gliT | EC 1.8.1.-; Gliotoxin biosynthesis protein T | Aspergillus fumigatus Af293 |
| Cytochrome P450 monooxygenase gliC | EC 1.-.-.-; Gliotoxin biosynthesis protein C | Aspergillus fumigatus Af293 |
| N-methyltransferase gliN | EC 2.1.1.-; Gliotoxin biosynthesis protein N | Aspergillus fumigatus Af293 |
| Compound | Description |
|---|
| hydronium ion | |
| Ammonium | |
| Manganese | A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035) |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| Pyruvic Acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |