Page last updated: 2024-10-06

flaviolin dimer and mompain biosynthesis

Proteins (6)

ProteinSynonymsTaxonomy
1,3,6,8-tetrahydroxynaphthalene synthaseTHNS; EC 2.3.1.233; 1,3,6,8-tetrahydroxynaphthalene synthesis polyketide synthase type III
1,3,6,8-tetrahydroxynaphthalene synthaseTHNS; EC 2.3.1.233; 1,3,6,8-tetrahydroxynaphthalene synthesis polyketide synthase type IIIStreptomyces griseus
1,3,6,8-tetrahydroxynaphthalene synthaseTHNS; EC 2.3.1.233; 1,3,6,8-tetrahydroxynaphthalene synthesis polyketide synthase type IIIStreptomyces coelicolor A3(2)
Biflaviolin synthase CYP158A2EC 1.14.19.69; Cytochrome P450 158A2; CYP158A2Streptomyces coelicolor A3(2)
Biflaviolin synthase CYP158A1EC 1.14.19.69; Cytochrome P450 158A1; CYP158A1Streptomyces coelicolor A3(2)
MomAStreptomyces antibioticus

Compounds (18)

CompoundDescription
hydronium ion
CobaltA trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis.
oxyquinolineAn antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.
NADH
CopperA heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55.
ironA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ManganeseA trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
IronA metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN.
ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn.
NickelA trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
1,10-phenanthrolineRN given refers to parent cpd; inhibits Zn-dependent metalloproteinases
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
Coenzyme A
1,3,6,8-tetrahydroxynaphthaleneintermediate in polyketide biosynthesis
Malonyl Coenzyme AA coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.