Page last updated: 2024-10-06

erythromycin D biosynthesis

Proteins (6)

ProteinSynonymsTaxonomy
6-deoxyerythronolide-B synthase EryA1, modules 1 and 2DEBS 1; EC 2.3.1.94; 6-deoxyerythronolide B synthase I; Erythronolide synthase; ORF CSaccharopolyspora erythraea
6-deoxyerythronolide-B synthase EryA2, modules 3 and 4DEBS 2; EC 2.3.1.94; 6-deoxyerythronolide B synthase II; Erythronolide synthase; ORF BSaccharopolyspora erythraea
6-deoxyerythronolide-B synthase EryA3, modules 5 and 6DEBS 3; EC 2.3.1.94; 6-deoxyerythronolide B synthase III; Erythronolide synthase; ORF CSaccharopolyspora erythraea
3-alpha-mycarosylerythronolide B desosaminyl transferaseEC 2.4.1.278; Desosaminyl transferase EryCIII; Erythromycin biosynthesis protein CIIISaccharopolyspora erythraea NRRL 2338
6-DEB TDP-mycarosyl glycosyltransferase Saccharopolyspora erythraea NRRL 2338
Cytochrome P450 family protein EryCIIErythromycin biosynthesis protein CIISaccharopolyspora erythraea NRRL 2338

Compounds (11)

CompoundDescription
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
6-deoxyerythronolide bStreptomyces erythreus metabolite; presumed intermediate in biosynthesis of erythromycins; structure given in first source
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
thymidine 5'-diphosphatesee also record for thymidine 3',5'-diphosphate, RN 2863-04-9
Coenzyme A
erythronolide bintermediate of erythromycin biogenesis; structure in first source
propionyl-coenzyme ARN given refers to parent cpd