Page last updated: 2024-10-06

de novo biosynthesis of pyrimidine ribonucleotides

Proteins (10)

ProteinSynonymsTaxonomy
Orotidine 5'-phosphate decarboxylaseEC 4.1.1.23; OMP decarboxylase; OMPDCase; OMPdecase; Uridine 5'-monophosphate synthase; UMP synthaseSaccharomyces cerevisiae S288C
Dihydroorotate dehydrogenase (fumarate)DHOD; DHODase; DHOdehase; EC 1.3.98.1; Dihydroorotate oxidaseSaccharomyces cerevisiae S288C
DihydroorotaseDHOase; EC 3.5.2.3Saccharomyces cerevisiae S288C
Uridylate kinaseUK; EC 2.7.4.14; ATP:UMP phosphotransferase; Deoxycytidylate kinase; CK; dCMP kinase; Suppressor of cdc8 protein; Uridine monophosphate kinase; UMP kinase; UMPKSaccharomyces cerevisiae S288C
CTP synthase 1EC 6.3.4.2; CTP synthetase 1; UTP--ammonia ligase 1Saccharomyces cerevisiae S288C
CTP synthase 2EC 6.3.4.2; CTP synthetase 2; UTP--ammonia ligase 2Saccharomyces cerevisiae S288C
Protein URA2Saccharomyces cerevisiae S288C
Orotate phosphoribosyltransferase 1OPRT 1; OPRTase 1; EC 2.4.2.10Saccharomyces cerevisiae S288C
Orotate phosphoribosyltransferase 2OPRT 2; OPRTase 2; EC 2.4.2.10Saccharomyces cerevisiae S288C
Nucleoside diphosphate kinaseNDK; NDP kinase; EC 2.7.4.6Saccharomyces cerevisiae S288C

Compounds (19)

CompoundDescription
diphosphoric acid
hydronium ion
Succinate
uridine diphosphateA uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Orthophosphate
Aspartate
fumaratesCompounds based on fumaric acid.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
Uridine TriphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
hydrogen carbonate
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
Carbamyl PhosphateThe monoanhydride of carbamic acid with PHOSPHORIC ACID. It is an important intermediate metabolite and is synthesized enzymatically by CARBAMYL-PHOSPHATE SYNTHASE (AMMONIA) and CARBAMOYL-PHOSPHATE SYNTHASE (GLUTAMINE-HYDROLYZING).
glutamate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
polyglutamineRN given for (D)-isomer
Cytidine TriphosphateCytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.
Uridine Monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
orotidylic acidstructure