Page last updated: 2024-10-06

cholesterol degradation to androstenedione I (cholesterol oxidase)

Proteins (14)

ProteinSynonymsTaxonomy
Medium/long-chain-fatty-acid--CoA/3-oxocholest-4-en-26-oate--CoA ligaseFACL; EC 6.2.1.2; EC 6.2.1.3; EC 6.2.1.42; Acyl-CoA synthetase; FACL19; Steroid-CoA ligase; Steroid-coenzyme A ligaseMycobacterium tuberculosis H37Rv
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomeraseCholesterol dehydrogenaseMycobacterium tuberculosis H37Rv
Cholesterol oxidaseCHOD; EC 1.1.3.6; Cholesterol isomerase; 5.3.3.1Brevibacterium sterolicum
3-oxocholest-4-en-26-oate--CoA ligaseEC 6.2.1.42; Steroid-CoA ligase; Steroid-coenzyme A ligaseRhodococcus rhodochrous
Conserved proteinMycobacterium tuberculosis H37Rv
Steroid 3-ketoacyl-CoA thiolaseEC 2.3.1.16; Acetyl-CoA acetyltransferase FadA5; Beta-ketoacyl-CoA thiolaseMycobacterium tuberculosis H37Rv
Acyl-CoA dehydrogenase FadE27ACAD; EC 1.3.99.-; 3-oxocholest-4-en-26-oyl-CoA dehydrogenase beta subunitMycobacterium tuberculosis H37Rv
Probable lipid transfer protein or keto acyl-CoA thiolase Ltp2Mycobacterium tuberculosis H37Rv
Acyl-CoA dehydrogenase FadE26ACAD; EC 1.3.99.-; 3-oxocholest-4-en-26-oyl-CoA dehydrogenase alpha subunitMycobacterium tuberculosis H37Rv
Uncharacterized proteinMycobacterium tuberculosis H37Rv
Possible enoyl-CoA hydratase EchA19 Mycobacterium tuberculosis H37Rv
Acyl-CoA dehydrogenase FadE28ACAD; EC 1.3.99.-; 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA dehydrogenase alpha subunit; 3-oxo-4-pregnene-20-carboxyl-CoA dehydrogenase alpha subunitMycobacterium tuberculosis H37Rv
Acyl-CoA dehydrogenase FadE29ACAD; EC 1.3.99.-; 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA dehydrogenase beta subunit; 3-oxo-4-pregnene-20-carboxyl-CoA dehydrogenase beta subunitMycobacterium tuberculosis H37Rv
Acyl-CoA dehydrogenase FadE34ACAD; EC 1.3.99.-; 3-oxochol-4-en-24-oyl-CoA dehydrogenaseMycobacterium tuberculosis H37Rv

Compounds (17)

CompoundDescription
diphosphoric acid
hydronium ion
NADH
CholesterolThe principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
adenosine monophosphateAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
cholest-5-en-3-one
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.
propionyl-coenzyme ARN given refers to parent cpd
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
androstenedioneA delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL.
cholest-4-en-3-one