Page last updated: 2024-10-06

butanol and isobutanol biosynthesis (engineered)

Proteins (13)

ProteinSynonymsTaxonomy
Pyruvate decarboxylase isozyme 1EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODCSaccharomyces cerevisiae S288C
Pyruvate decarboxylase isozyme 2EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODCSaccharomyces cerevisiae S288C
Pyruvate decarboxylase isozyme 3EC 4.1.1.-; EC 4.1.1.43; EC 4.1.1.72; EC 4.1.1.74; Thiamine pyrophosphate-dependent 2-oxo-acid decarboxylase; 2ODCSaccharomyces cerevisiae S288C
Glycine oxidaseGO; EC 1.4.3.19Bacillus subtilis subsp. subtilis str. 168
S-(hydroxymethyl)glutathione dehydrogenaseEC 1.1.1.284; Alcohol dehydrogenase SFA; 1.1.1.1; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; FLD; GSH-FDH; 1.1.1.-Saccharomyces cerevisiae S288C
Alcohol dehydrogenase 1EC 1.1.1.1; Alcohol dehydrogenase I; YADH-1Saccharomyces cerevisiae S288C
Alcohol dehydrogenase 2EC 1.1.1.1; Alcohol dehydrogenase II; YADH-2Saccharomyces cerevisiae S288C
Alcohol dehydrogenase 3, mitochondrialEC 1.1.1.1; Alcohol dehydrogenase III; YADH-3Saccharomyces cerevisiae S288C
Alcohol dehydrogenase 4EC 1.1.1.1; Alcohol dehydrogenase IV; ADHIVSaccharomyces cerevisiae S288C
Alcohol dehydrogenase 5EC 1.1.1.1; Alcohol dehydrogenase VSaccharomyces cerevisiae S288C
3-isopropylmalate dehydrogenase3-IPM-DH; IMDH; EC 1.1.1.85; Beta-IPM dehydrogenaseSaccharomyces cerevisiae S288C
Malate synthase 2EC 2.3.3.9; Degradation of allantoin protein 7Saccharomyces cerevisiae S288C
Malate synthase 1EC 2.3.3.9Saccharomyces cerevisiae S288C

Compounds (17)

CompoundDescription
hydronium ion
NADH
Ammonium
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
nadA coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed)
butyraldehyde
1-butanolA four carbon linear hydrocarbon that has a hydroxy group at position 1.
glyoxylate
alpha-keto-isovaleric acid
2-ketovalerate
Coenzyme A
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)
isobutyl alcoholRN given refers to parent cpd
isobutyraldehyde