| Protein | Synonyms | Taxonomy |
|---|
| Nicotinate-nucleotide adenylyltransferase | EC 2.7.7.18; Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase | Escherichia coli K-12 |
| Bifunctional aspartokinase/homoserine dehydrogenase 1 | Aspartokinase I/homoserine dehydrogenase I; AKI-HDI | Escherichia coli K-12 |
| Homoserine kinase | HK; HSK; EC 2.7.1.39 | Escherichia coli K-12 |
| 4-hydroxy-tetrahydrodipicolinate synthase | HTPA synthase; EC 4.3.3.7 | Escherichia coli K-12 |
| Acetylornithine/succinyldiaminopimelate aminotransferase | ACOAT; DapATase; Succinyldiaminopimelate transferase; EC 2.6.1.11; EC 2.6.1.17 | Escherichia coli K-12 |
| Quinolinate synthase A | EC 2.5.1.72 | Escherichia coli K-12 |
| Aspartate aminotransferase | AspAT; EC 2.6.1.1; Transaminase A | Escherichia coli K-12 |
| Lysine-sensitive aspartokinase 3 | EC 2.7.2.4; Aspartate kinase III; AKIII; Lysine-sensitive aspartokinase III | Escherichia coli K-12 |
| L-aspartate oxidase | LASPO; EC 1.4.3.16; Quinolinate synthase B | Escherichia coli K-12 |
| 4-hydroxy-tetrahydrodipicolinate reductase | HTPA reductase; EC 1.17.1.8 | Escherichia coli K-12 |
| Diaminopimelate decarboxylase | DAP decarboxylase; DAPDC; EC 4.1.1.20 | Escherichia coli K-12 |
| Diaminopimelate epimerase | DAP epimerase; EC 5.1.1.7; PLP-independent amino acid racemase | Escherichia coli K-12 |
| Phosphoserine aminotransferase | EC 2.6.1.52; Phosphohydroxythreonine aminotransferase; PSAT | Escherichia coli K-12 |
| S-adenosylmethionine synthase | AdoMet synthase; EC 2.5.1.6; MAT; Methionine adenosyltransferase | Escherichia coli K-12 |
| Cystathionine gamma-synthase | CGS; EC 2.5.1.48; O-succinylhomoserine (thiol)-lyase | Escherichia coli K-12 |
| Homoserine O-succinyltransferase | HST; EC 2.3.1.46; Homoserine transsuccinylase; HTS | Escherichia coli K-12 |
| 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | EC 2.1.1.14; Cobalamin-independent methionine synthase; Methionine synthase, vitamin-B12 independent isozyme | Escherichia coli K-12 |
| Threonine synthase | TS; EC 4.2.3.1 | Escherichia coli K-12 |
| NH(3)-dependent NAD(+) synthetase | EC 6.3.1.5; Nicotinamide adenine dinucleotide synthetase; NADS; Nitrogen regulatory protein | Escherichia coli K-12 |
| Methionine synthase | EC 2.1.1.13; 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12-dependent; MS | Escherichia coli K-12 |
| Bifunctional aspartokinase/homoserine dehydrogenase 2 | Aspartokinase II/homoserine dehydrogenase II; AKII-HDII | Escherichia coli K-12 |
| 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase | EC 2.3.1.117; Succinyl-CoA: tetrahydrodipicolinate N-succinyltransferase; Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase | Escherichia coli K-12 |
| Aspartate-semialdehyde dehydrogenase | ASA dehydrogenase; ASADH; EC 1.2.1.11; Aspartate-beta-semialdehyde dehydrogenase | Escherichia coli K-12 |
| Succinyl-diaminopimelate desuccinylase | SDAP desuccinylase; EC 3.5.1.18; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase | Escherichia coli K-12 |
| Nicotinate-nucleotide pyrophosphorylase [carboxylating] | EC 2.4.2.19; Quinolinate phosphoribosyltransferase [decarboxylating]; QAPRTase | Escherichia coli K-12 |
| Compound | Description |
|---|
| diphosphoric acid | |
| hydronium ion | |
| Cobalt | A trace element that is a component of vitamin B12. It has the atomic symbol Co, atomic number 27, and atomic weight 58.93. It is used in nuclear weapons, alloys, and pigments. Deficiency in animals leads to anemia; its excess in humans can lead to erythrocytosis. |
| Succinate | |
| Ammonium | |
| Copper | A heavy metal trace element with the atomic symbol Cu, atomic number 29, and atomic weight 63.55. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| dimercaprol | An anti-gas warfare agent that is effective against Lewisite (dichloro(2-chlorovinyl)arsine) and formerly known as British Anti-Lewisite or BAL. It acts as a chelating agent and is used in the treatment of arsenic, gold, and other heavy metal poisoning. |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| Aspartate | |
| adenosine | A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| boric acid | |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| potassium | An element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Sodium | A member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| succinyl-coenzyme A | |
| Adenylyl Imidodiphosphate | 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. |
| iodoacetamide | An alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate. |
| Pyruvic Acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| dioxouranium(vi) | |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| alpha-Ketoglutarate | |
| Oxaloacetate | An anionic form of oxaloacetic acid. |
| diethyl pyrocarbonate | Preservative for wines, soft drinks, and fruit juices and a gentle esterifying agent. |
| triphosphate | |
| ethylmaleimide | A sulfhydryl reagent that is widely used in experimental biochemical studies. |
| 2,6-pyridine dicarboxylate | |
| Edetic Acid | A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive. |
| aspartic semialdehyde | RN given refers to cpd without isomeric designation |
| maleate | |
| glutamate | |
| Quinolinate | |
| fructose-1,6-diphosphate | RN refers to (D)-isomer |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| cordycepin | |
| Cysteine | A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. |
| polyglutamine | RN given for (D)-isomer |
| bromopyruvate | |
| hydroxylamine | A colorless inorganic compound (HONH2) used in organic synthesis and as a reducing agent, due to its ability to donate nitric oxide. |
| phthalate | |
| iminoaspartate | |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| Coenzyme A | |
| nicotinic acid adenine dinucleotide | intermediate in the biosynthesis of NAD |
| 4-phosphothreonine | structure in first source |
| nicotinate mononucleotide | |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |
| 2-amino-4-oxo-5-chloropentanoate | inhibitor of asparagine synthetase; structure |