Page last updated: 2024-10-06

aclacinomycin biosynthesis

Proteins (14)

ProteinSynonymsTaxonomy
Aclacinomycin-N/aclacinomycin-A oxidaseAknOx; EC 1.1.3.45; EC 1.3.3.14; Aclacinomycin oxidoreductaseStreptomyces galilaeus
AknAStreptomyces galilaeus
Aclacinomycin-T 2-deoxy-L-fucose transferaseAknK; EC 2.4.1.327; L-2-deoxyfucosyltransferaseStreptomyces galilaeus
Aklavinone 7-beta-L-rhodosaminyltransferaseEC 2.4.1.326Streptomyces galilaeus
AknGStreptomyces galilaeus
AknE1Streptomyces galilaeus
AknFStreptomyces galilaeus
AknBStreptomyces galilaeus
Aklanonic acid methyl ester cyclase AcmAAAME cyclase; EC 5.5.1.23; Methyl aklanonate cyclaseStreptomyces galilaeus
AknE2Streptomyces galilaeus
AknXStreptomyces galilaeus
Putative aklaviketone reductaseStreptomyces galilaeus
AknDStreptomyces galilaeus
AknCStreptomyces galilaeus

Compounds (19)

CompoundDescription
hydronium ion
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
Hydrogen PeroxideA strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials.
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
AclarubicinAn anthracycline produced by Streptomyces galilaeus. It has potent antineoplastic activity.
aclacinomycin Y
aclacinomycin N
aklavinantibiotic prepared from culture liquids of streptomycete (A 1129); possessing antiphage activity; structure
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
aklavinonefrom Streptomyces galilaeus MA 144-M1, strain 3AR-33; structure in first source
NADPNicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed)
thymidine 5'-diphosphatesee also record for thymidine 3',5'-diphosphate, RN 2863-04-9
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Coenzyme A
S 383-Y
Malonyl Coenzyme AA coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems.
propionyl-coenzyme ARN given refers to parent cpd
Flavin-Adenine DinucleotideA condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972)