Page last updated: 2024-10-06

Vitamin B6-dependent and responsive disorders

Proteins (2)

ProteinSynonymsTaxonomy
Pyridoxal kinaseEC 2.7.1.35; Pyridoxine kinaseHomo sapiens (human)
Pyridoxal phosphate homeostasis proteinPLP homeostasis protein; Proline synthase co-transcribed bacterial homolog protein; Pyridoxal phosphate-binding proteinHomo sapiens (human)

Compounds (14)

CompoundDescription
pyridoxalThe 4-carboxyaldehyde form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid.
pyridoxal phosphateThis is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxineThe 4-methanol form of VITAMIN B 6 which is converted to PYRIDOXAL PHOSPHATE which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).
pyridoxine 5-phosphateRN given refers to parent cpd
lysineAn essential amino acid. It is often added to animal feed.
pyridoxamine phosphateRN given refers to parent cpd; structure
delta-1-pyrroline-5-carboxylate(L)-isomer is the biologically active form; RN given refers to cpd without isomeric designation; structure
prolineA non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.
saccharopinelysine precursor in the aminoadipic acid-lysine pathway in yeast; minor descriptor (75-85); on-line & Index Medicus search LYSINE/analogs & derivatives (75-85); RN given refers to (L)-isomer
allysinestructure
pipecolic acidRN given refers to cpd without isomeric designation
5'-O-(glucopyranosyl)pyridoxineRN given refers to (D)-isomer
2-aminoadipic acidA metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
glutamate