Pathways > Vitamin B1 (thiamin) metabolism
Page last updated: 2024-10-06
Vitamin B1 (thiamin) metabolism
Proteins (3)
| Protein | Synonyms | Taxonomy |
|---|
| Thiamin pyrophosphokinase 1 | hTPK1; EC 2.7.6.2; Placental protein 20; PP20; Thiamine pyrophosphokinase 1 | Homo sapiens (human) |
| Thiamine-triphosphatase | ThTPase; EC 3.6.1.28 | Homo sapiens (human) |
| Mitochondrial thiamine pyrophosphate carrier | Mitochondrial uncoupling protein 1; Solute carrier family 25 member 19 | Homo sapiens (human) |
Compounds (9)
| Compound | Description |
|---|
| thiamine | 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride. |
| Thiamine Pyrophosphate | The coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the PYRUVATE DEHYDROGENASE COMPLEX and the KETOGLUTARATE DEHYDROGENASE COMPLEX. |
| Orthophosphate | |
| Thiamine Triphosphate | 3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-4-methyl-5-(4,6,8,8-tetrahydroxy-3,5,7-trioxa-4,6,8-triphosphaoct-1-yl)thiazolium hydroxide, inner salt, P,P',P''-trioxide. The triphosphate ester of thiamine. In Leigh's disease, this compound is present in decreased amounts in the brain due to a metabolic block in its formation. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |