Page last updated: 2024-10-06

Virus replication cycle (COVID-19 Disease Map)

Proteins (24)

ProteinSynonymsTaxonomy
Replicase polyprotein 1app1a; ORF1a polyproteinSevere acute respiratory syndrome coronavirus 2
NucleoproteinN; Nucleocapsid protein; NC; Protein NSevere acute respiratory syndrome coronavirus 2
Cathepsin BEC 3.4.22.1; APP secretase; APPS; Cathepsin B1Homo sapiens (human)
Procathepsin LEC 3.4.22.15; Cathepsin L1; Major excreted protein; MEPHomo sapiens (human)
FurinEC 3.4.21.75; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACEHomo sapiens (human)
Sigma non-opioid intracellular receptor 1Aging-associated gene 8 protein; SR31747-binding protein; SR-BP; Sigma 1-type opioid receptor; SIG-1R; Sigma1-receptor; Sigma1R; hSigmaR1Homo sapiens (human)
Angiotensin-converting enzyme 2 EC 3.4.17.23; Angiotensin-converting enzyme homolog; ACEH; Angiotensin-converting enzyme-related carboxypeptidase; ACE-related carboxypeptidase; 3.4.17.-; Metalloprotease MPROT15Homo sapiens (human)
Spike glycoproteinS glycoprotein; E2; Peplomer proteinSevere acute respiratory syndrome coronavirus 2
Replicase polyprotein 1abpp1ab; ORF1ab polyproteinSevere acute respiratory syndrome coronavirus 2
Neuropilin-1Vascular endothelial cell growth factor 165 receptorHomo sapiens (human)
Transmembrane protease serine 2EC 3.4.21.-; Serine protease 10Homo sapiens (human)
Insulin-degrading enzymeEC 3.4.24.56; Abeta-degrading protease; Insulin protease; Insulinase; InsulysinHomo sapiens (human)
V-type proton ATPase subunit S1V-ATPase subunit S1; Protein XAP-3; V-ATPase Ac45 subunit; V-ATPase S1 accessory protein; Vacuolar proton pump subunit S1Homo sapiens (human)
ORF8 proteinORF8; Non-structural protein 8; ns8Severe acute respiratory syndrome coronavirus 2
Membrane proteinM; E1 glycoprotein; Matrix glycoprotein; Membrane glycoproteinSevere acute respiratory syndrome coronavirus 2
ORF3a proteinORF3a; Accessory protein 3a; Protein 3a; Protein U274; Protein X1Severe acute respiratory syndrome coronavirus 2
ORF6 proteinORF6; Accessory protein 6; Non-structural protein 6; ns6; Protein X3Severe acute respiratory syndrome coronavirus 2
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferaseEC 2.4.1.131; Asparagine-linked glycosylation protein 11 homolog; Glycolipid 2-alpha-mannosyltransferaseHomo sapiens (human)
Nuclear pore membrane glycoprotein 210Nuclear pore protein gp210; Nuclear envelope pore membrane protein POM 210; POM210; Nucleoporin Nup210; Pore membrane protein of 210 kDaHomo sapiens (human)
ORF9c proteinORF9c; Uncharacterized protein 14; ORF14Severe acute respiratory syndrome coronavirus 2
ORF7b proteinORF7b; Accessory protein 7bSevere acute respiratory syndrome coronavirus 2
Envelope small membrane proteinE; sM proteinSevere acute respiratory syndrome coronavirus 2
ORF7a proteinORF7a; Accessory protein 7a; Protein U122; Protein X4Severe acute respiratory syndrome coronavirus 2
ORF9b proteinORF9b; Accessory protein 9b; ORF-9b; Protein 9bSevere acute respiratory syndrome coronavirus 2

Compounds (5)

CompoundDescription
hydronium ion
camostat
CholesterolThe principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
selinexorinhibits karyopherin XPO1
bafilomycin a1from Streptomyces griseus; structure given in first source