Page last updated: 2024-10-06

Vemurafenib Pathway, Pharmacodynamics

Proteins (11)

ProteinSynonymsTaxonomy
Son of sevenless homolog 2SOS-2Homo sapiens (human)
Epidermal growth factor receptorEC 2.7.10.1; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1Homo sapiens (human)
RAF proto-oncogene serine/threonine-protein kinaseEC 2.7.11.1; Proto-oncogene c-RAF; cRaf; Raf-1Homo sapiens (human)
Serine/threonine-protein kinase B-rafEC 2.7.11.1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1Homo sapiens (human)
Dual specificity mitogen-activated protein kinase kinase 2MAP kinase kinase 2; MAPKK 2; EC 2.7.12.2; ERK activator kinase 2; MAPK/ERK kinase 2; MEK 2Homo sapiens (human)
Son of sevenless homolog 1SOS-1Homo sapiens (human)
Fibroblast growth factor 2FGF-2; Basic fibroblast growth factor; bFGF; Heparin-binding growth factor 2; HBGF-2Homo sapiens (human)
Serine/threonine-protein kinase A-RafEC 2.7.11.1; Proto-oncogene A-Raf; Proto-oncogene A-Raf-1; Proto-oncogene PksHomo sapiens (human)
Ras-related protein M-RasEC 3.6.5.2; Ras-related protein R-Ras3Homo sapiens (human)
Growth factor receptor-bound protein 2 Homo sapiens (human)
cDNA FLJ75737, highly similar to Homo sapiens v-ets erythroblastosis virus E26 oncogene homolog 1 Homo sapiens (human)

Compounds (1)

CompoundDescription
plx4032