| Protein | Synonyms | Taxonomy |
|---|
| Trifunctional enzyme subunit alpha, mitochondrial | 78 kDa gastrin-binding protein; Monolysocardiolipin acyltransferase; 2.3.1.-; TP-alpha | Homo sapiens (human) |
| 3-hydroxyacyl-CoA dehydrogenase type-2 | EC 1.1.1.35; 17-beta-estradiol 17-dehydrogenase; 1.1.1.62; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+)); 1.1.1.239; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 1.1.1.178; 3-hydroxyacyl-CoA deh | Homo sapiens (human) |
| Cytochrome P450 2C9 | EC 1.14.14.1; (R)-limonene 6-monooxygenase; 1.14.14.53; (S)-limonene 6-monooxygenase; 1.14.14.51; (S)-limonene 7-monooxygenase; 1.14.14.52; CYPIIC9; Cholesterol 25-hydroxylase; Cytochrome P-450MP; Cytochrome P450 MP-4; Cytochrome P450 MP-8; Cytochrome P45 | Homo sapiens (human) |
| Cytochrome P450 2B6 | EC 1.14.13.-; 1,4-cineole 2-exo-monooxygenase; CYPIIB6; Cytochrome P450 IIB1 | Homo sapiens (human) |
| Trifunctional enzyme subunit beta, mitochondrial | TP-beta | Homo sapiens (human) |
| Cytochrome P450 2A6 | EC 1.14.13.-; 1,4-cineole 2-exo-monooxygenase; CYPIIA6; Coumarin 7-hydroxylase; Cytochrome P450 IIA3; Cytochrome P450(I) | Homo sapiens (human) |
| UDP-glucuronosyltransferase 1A3 | UGT1A3; EC 2.4.1.17; UDP-glucuronosyltransferase 1-3; UDPGT 1-3; UGT1*3; UGT1-03; UGT1.3; UDP-glucuronosyltransferase 1-C; UGT-1C; UGT1C; UDP-glucuronosyltransferase 1A isoform 3 | Homo sapiens (human) |
| Peroxisomal bifunctional enzyme | PBE; PBFE; L-bifunctional protein; LBP; Multifunctional enzyme 1; MFE1 | Homo sapiens (human) |
| Isovaleryl-CoA dehydrogenase, mitochondrial | IVD; EC 1.3.8.4; Butyryl-CoA dehydrogenase; 1.3.8.1 | Homo sapiens (human) |
| Acyl-coenzyme A synthetase ACSM1, mitochondrial | EC 6.2.1.2; Acyl-CoA synthetase medium-chain family member 1; Benzoate--CoA ligase; 6.2.1.25; Butyrate--CoA ligase 1; Butyryl-coenzyme A synthetase 1; Lipoate-activating enzyme; Middle-chain acyl-CoA synthetase 1; Xenobiotic/medium-chain fatty acid-CoA li | Homo sapiens (human) |
| Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial | SBCAD; EC 1.3.8.5; 2-methyl branched chain acyl-CoA dehydrogenase; 2-MEBCAD; 2-methylbutyryl-coenzyme A dehydrogenase; 2-methylbutyryl-CoA dehydrogenase | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| valproic acid | A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS. |
| NADH | |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| uridine diphosphate | A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| Coenzyme A | |
| 2-propyl-4-pentenoic acid | putative toxic metabolite of valproic acid |
| 5-hydroxyvalproate | |
| uridine diphosphate glucuronic acid | A nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| trans-2-en-valproate | |
| 2-propyl-2,4-pentadienoic acid | toxic metabolite of valproic acid; RN given refers to cpd without isomeric designation |
| 4-hydroxyvalproate | RN given refers to compound with no isomeric designation |
| 2-n-propyl-3-oxopentanoic acid | structure given in first source |
| delta(3) valproic acid | structure in first source |
| creolin | from refined coal tar oils |
| pyrophosphate | |
| valproic acid glucuronide | major metabolite of valproic acid |