Page last updated: 2024-10-06

Validated transcriptional targets of deltaNp63 isoforms

Proteins (48)

ProteinSynonymsTaxonomy
T-box transcription factor TBrachyury protein; Protein THomo sapiens (human)
POU domain, class 2, transcription factor 2Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2Homo sapiens (human)
Runt-related transcription factor 1Acute myeloid leukemia 1 protein; Core-binding factor subunit alpha-2; CBF-alpha-2; Oncogene AML-1; Polyomavirus enhancer-binding protein 2 alpha B subunit; PEA2-alpha B; PEBP2-alpha B; SL3-3 enhancer factor 1 alpha B subunit; SL3/AKV core-binding factor Homo sapiens (human)
Transcriptional coactivator YAP1Yes-associated protein 1; Protein yorkie homolog; Yes-associated protein YAP65 homologHomo sapiens (human)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoformPP2A B subunit isoform B'-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PR61alpha; PP2A B subunit isoform R5-alphaHomo sapiens (human)
Vitamin D3 receptorVDR; 1,25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1Homo sapiens (human)
Tyrosine-protein kinase receptor UFOEC 2.7.10.1; AXL oncogeneHomo sapiens (human)
Fatty acid synthaseEC 2.3.1.85; Type I fatty acid synthaseHomo sapiens (human)
Glycogen synthase kinase-3 betaGSK-3 beta; EC 2.7.11.26; Serine/threonine-protein kinase GSK3B; 2.7.11.1Homo sapiens (human)
Breast cancer type 2 susceptibility proteinFanconi anemia group D1 proteinHomo sapiens (human)
Double-strand break repair protein MRE11EC 3.1.-.-; Double-strand break repair protein MRE11A; Meiotic recombination 11 homolog 1; MRE11 homolog 1; Meiotic recombination 11 homolog A; MRE11 homolog AHomo sapiens (human)
G2/mitotic-specific cyclin-B2Homo sapiens (human)
DNA topoisomerase 2-alphaEC 5.6.2.2; DNA topoisomerase II, alpha isozymeHomo sapiens (human)
Integrin alpha-3CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alphaHomo sapiens (human)
B2 bradykinin receptorB2R; BK-2 receptorHomo sapiens (human)
E3 ubiquitin-protein ligase Mdm2EC 2.3.2.27; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; RING-type E3 ubiquitin transferase Mdm2; p53-binding protein Mdm2Homo sapiens (human)
E3 ubiquitin-protein ligase Itchy homologItch; EC 2.3.2.26; Atrophin-1-interacting protein 4; AIP4; HECT-type E3 ubiquitin transferase Itchy homolog; NFE2-associated polypeptide 1; NAPP1Homo sapiens (human)
Insulin-like growth factor-binding protein 3IBP-3; IGF-binding protein 3; IGFBP-3Homo sapiens (human)
14-3-3 protein sigmaEpithelial cell marker protein 1; StratifinHomo sapiens (human)
Cyclin-dependent kinase inhibitor 2ACyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a; p16-INK4; p16INK4AHomo sapiens (human)
Adenosine deaminaseEC 3.5.4.4; Adenosine aminohydrolaseHomo sapiens (human)
Serine-protein kinase ATMEC 2.7.11.1; Ataxia telangiectasia mutated; A-T mutatedHomo sapiens (human)
Keratin, type II cytoskeletal 558 kDa cytokeratin; Cytokeratin-5; CK-5; Keratin-5; K5; Type-II keratin Kb5Homo sapiens (human)
Tumor protein 63p63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor KET; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p40; p51Homo sapiens (human)
F-box/WD repeat-containing protein 7Archipelago homolog; hAgo; F-box and WD-40 domain-containing protein 7; F-box protein FBX30; SEL-10; hCdc4Homo sapiens (human)
Neurogenic locus notch homolog protein 1Notch 1; hN1; Translocation-associated notch protein TAN-1Homo sapiens (human)
Proteasomal ubiquitin receptor ADRM1110 kDa cell membrane glycoprotein; Gp110; Adhesion-regulating molecule 1; ARM-1; Proteasome regulatory particle non-ATPase 13; hRpn13; Rpn13 homologHomo sapiens (human)
Transcription factor HES-1Class B basic helix-loop-helix protein 39; bHLHb39; Hairy and enhancer of split 1; Hairy homolog; Hairy-like protein; hHLHomo sapiens (human)
Tumor suppressor ARFAlternative reading frame; ARF; Cyclin-dependent kinase inhibitor 2A; p14ARFHomo sapiens (human)
Keratin, type I cytoskeletal 14Cytokeratin-14; CK-14; Keratin-14; K14Homo sapiens (human)
SEC14-like protein 2Alpha-tocopherol-associated protein; TAP; hTAP; Squalene transfer protein; Supernatant protein factor; SPFHomo sapiens (human)
GTP-binding protein RADRAD1; Ras associated with diabetesHomo sapiens (human)
HMG box-containing protein 1HMG box transcription factor 1; High mobility group box transcription factor 1Homo sapiens (human)
CCAAT/enhancer-binding protein deltaC/EBP delta; Nuclear factor NF-IL6-beta; NF-IL6-betaHomo sapiens (human)
Pro-neuregulin-1, membrane-bound isoformPro-NRG1Homo sapiens (human)
Interleukin-1 alphaIL-1 alpha; Hematopoietin-1Homo sapiens (human)
Fos-related antigen 2 FRA-2Homo sapiens (human)
Collagen alpha-1(V) chainHomo sapiens (human)
Homeobox protein DLX-5Homo sapiens (human)
Homeobox protein DLX-6Homo sapiens (human)
Ras-related protein Rab-38Melanoma antigen NY-MEL-1Homo sapiens (human)
Receptor of activated protein C kinase 1Cell proliferation-inducing gene 21 protein; Guanine nucleotide-binding protein subunit beta-2-like 1; Guanine nucleotide-binding protein subunit beta-like protein 12.3; Human lung cancer oncogene 7 protein; HLC-7; Receptor for activated C kinase; Small rHomo sapiens (human)
Syntaxin-binding protein 4Syntaxin 4-interacting protein; STX4-interacting protein; SynipHomo sapiens (human)
p53 apoptosis effector related to PMP-22Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THWHomo sapiens (human)
NEDD4-like E3 ubiquitin-protein ligase WWP1EC 2.3.2.26; Atrophin-1-interacting protein 5; AIP5; HECT-type E3 ubiquitin transferase WWP1; TGIF-interacting ubiquitin ligase 1; Tiul1; WW domain-containing protein 1Homo sapiens (human)
Transcription factor 7-like 1HMG box transcription factor 3; TCF-3Homo sapiens (human)
Lymphoid-specific helicaseEC 3.6.4.-; Proliferation-associated SNF2-like protein; SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6Homo sapiens (human)
Glutathione peroxidase 2GPx-2; GSHPx-2; EC 1.11.1.9; Gastrointestinal glutathione peroxidase; Glutathione peroxidase-gastrointestinal; GPx-GI; GSHPx-GI; Glutathione peroxidase-related protein 2; GPRP-2Homo sapiens (human)

Compounds (0)

CompoundDescription