Page last updated: 2024-10-06

Validated transcriptional targets of TAp63 isoforms

Proteins (54)

ProteinSynonymsTaxonomy
Phorbol-12-myristate-13-acetate-induced protein 1PMA-induced protein 1; Immediate-early-response protein APR; Protein NoxaHomo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit betaI-kappa-B-kinase beta; IKK-B; IKK-beta; IkBKB; EC 2.7.11.10; I-kappa-B kinase 2; IKK2; Nuclear factor NF-kappa-B inhibitor kinase beta; NFKBIKB; Serine/threonine protein kinase IKBKB; 2.7.11.1Homo sapiens (human)
Inhibitor of nuclear factor kappa-B kinase subunit alphaI-kappa-B kinase alpha; IKK-A; IKK-alpha; IkBKA; IkappaB kinase; EC 2.7.11.10; Conserved helix-loop-helix ubiquitous kinase; I-kappa-B kinase 1; IKK1; Nuclear factor NF-kappa-B inhibitor kinase alpha; NFKBIKA; Transcription factor 16; TCF-16Homo sapiens (human)
Tyrosine-protein kinase ABL1EC 2.7.10.2; Abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Proto-oncogene c-Abl; p150Homo sapiens (human)
Vitamin D3 receptorVDR; 1,25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1Homo sapiens (human)
Serine/threonine-protein kinase PLK1EC 2.7.11.21; Polo-like kinase 1; PLK-1; Serine/threonine-protein kinase 13; STPK13Homo sapiens (human)
Calcium-activated chloride channel regulator 2EC 3.4.-.-; Calcium-activated chloride channel family member 2; hCLCA2; Calcium-activated chloride channel protein 3; CaCC-3; hCaCC-3Homo sapiens (human)
NADEC 1.6.5.2; Azoreductase; DT-diaphorase; DTD; Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; QR1Homo sapiens (human)
Integrin alpha-3CD49 antigen-like family member C; FRP-2; Galactoprotein B3; GAPB3; VLA-3 subunit alphaHomo sapiens (human)
E3 ubiquitin-protein ligase Mdm2EC 2.3.2.27; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; RING-type E3 ubiquitin transferase Mdm2; p53-binding protein Mdm2Homo sapiens (human)
Protein kinase C delta typeEC 2.7.11.13; Tyrosine-protein kinase PRKCD; 2.7.10.2; nPKC-deltaHomo sapiens (human)
Apoptosis regulator BAX Bcl-2-like protein 4; Bcl2-L-4Homo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
14-3-3 protein theta14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1Homo sapiens (human)
E3 ubiquitin-protein ligase Itchy homologItch; EC 2.3.2.26; Atrophin-1-interacting protein 4; AIP4; HECT-type E3 ubiquitin transferase Itchy homolog; NFE2-associated polypeptide 1; NAPP1Homo sapiens (human)
Insulin-like growth factor-binding protein 3IBP-3; IGF-binding protein 3; IGFBP-3Homo sapiens (human)
Bcl-2-binding component 3, isoforms 1/2JFY-1; p53 up-regulated modulator of apoptosisHomo sapiens (human)
Endoribonuclease DicerEC 3.1.26.3; Helicase with RNase motif; Helicase MOIHomo sapiens (human)
Tumor necrosis factor receptor superfamily member 6Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptorHomo sapiens (human)
Adenosine deaminaseEC 3.5.4.4; Adenosine aminohydrolaseHomo sapiens (human)
Cyclin-dependent kinase inhibitor 1CDK-interacting protein 1; Melanoma differentiation-associated protein 6; MDA-6; p21Homo sapiens (human)
Sonic hedgehog proteinSHH; HHG-1; Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains; ShhNCHomo sapiens (human)
Transcription factor Sp1Homo sapiens (human)
Protein jagged-1Jagged1; hJ1Homo sapiens (human)
Growth/differentiation factor 15GDF-15; Macrophage inhibitory cytokine 1; MIC-1; NSAID-activated gene 1 protein; NAG-1; NSAID-regulated gene 1 protein; NRG-1; Placental TGF-beta; Placental bone morphogenetic protein; Prostate differentiation factorHomo sapiens (human)
Tumor protein 63p63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor KET; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p40; p51Homo sapiens (human)
LactadherinBreast epithelial antigen BA46; HMFG; MFGM; Milk fat globule-EGF factor 8; MFG-E8; SED1Homo sapiens (human)
TNF receptor-associated factor 4Cysteine-rich domain associated with RING and Traf domains protein 1; Metastatic lymph node gene 62 protein; MLN 62; RING finger protein 83Homo sapiens (human)
N-glycosylase/DNA lyaseHomo sapiens (human)
Protein PMLPromyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19Homo sapiens (human)
Dystonin230 kDa bullous pemphigoid antigen; 230/240 kDa bullous pemphigoid antigen; Bullous pemphigoid antigen 1; BPA; Bullous pemphigoid antigen; Dystonia musculorum protein; Hemidesmosomal plaque proteinHomo sapiens (human)
Tumor suppressor ARFAlternative reading frame; ARF; Cyclin-dependent kinase inhibitor 2A; p14ARFHomo sapiens (human)
Transcription factor AP-2 gammaAP2-gamma; Activating enhancer-binding protein 2 gamma; Transcription factor ERF-1Homo sapiens (human)
NADPH:adrenodoxin oxidoreductase, mitochondrialAR; Adrenodoxin reductase; EC 1.18.1.6; Ferredoxin--NADP(+) reductase; Ferredoxin reductaseHomo sapiens (human)
E3 SUMO-protein ligase EGR2EC 2.3.2.-; AT591; E3 SUMO-protein transferase ERG2; Early growth response protein 2; EGR-2; Zinc finger protein Krox-20Homo sapiens (human)
Envoplakin210 kDa cornified envelope precursor protein; 210 kDa paraneoplastic pemphigus antigen; p210Homo sapiens (human)
HMG box-containing protein 1HMG box transcription factor 1; High mobility group box transcription factor 1Homo sapiens (human)
Short-chain dehydrogenase/reductase 3EC 1.1.1.300; DD83.1; Retinal short-chain dehydrogenase/reductase 1; retSDR1; Retinol dehydrogenase 17; Short chain dehydrogenase/reductase family 16C member 1Homo sapiens (human)
Integrin beta-4GP150Homo sapiens (human)
Growth arrest and DNA damage-inducible protein GADD45 alphaDNA damage-inducible transcript 1 protein; DDIT-1Homo sapiens (human)
Protein S100-A2CAN19; Protein S-100L; S100 calcium-binding protein A2Homo sapiens (human)
Serpin B5Maspin; Peptidase inhibitor 5; PI-5Homo sapiens (human)
FACT complex subunit SSRP1Chromatin-specific transcription elongation factor 80 kDa subunit; Facilitates chromatin transcription complex 80 kDa subunit; FACT 80 kDa subunit; FACTp80; Facilitates chromatin transcription complex subunit SSRP1; Recombination signal sequence recognitiHomo sapiens (human)
Flotillin-2Epidermal surface antigen; ESA; Membrane component chromosome 17 surface marker 1Homo sapiens (human)
Quinone oxidoreductase PIG3EC 1.-.-.-; Tumor protein p53-inducible protein 3; p53-induced gene 3 proteinHomo sapiens (human)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 360 kDa BRG-1/Brm-associated factor subunit C; BRG1-associated factor 60C; BAF60CHomo sapiens (human)
Mitochondria-eating proteinSpermatogenesis-associated protein 18Homo sapiens (human)
CDK5 and ABL1 enzyme substrate 1Interactor with CDK3 1; Ik3-1Homo sapiens (human)
Apoptosis-enhancing nucleaseEC 3.1.-.-; Interferon-stimulated 20 kDa exonuclease-like 1Homo sapiens (human)
p53 apoptosis effector related to PMP-22Keratinocyte-associated protein 1; KCP-1; P53-induced protein PIGPC1; Transmembrane protein THWHomo sapiens (human)
NEDD4-like E3 ubiquitin-protein ligase WWP1EC 2.3.2.26; Atrophin-1-interacting protein 5; AIP5; HECT-type E3 ubiquitin transferase WWP1; TGIF-interacting ubiquitin ligase 1; Tiul1; WW domain-containing protein 1Homo sapiens (human)
F-box/WD repeat-containing protein 1AE3RSIkappaB; Epididymis tissue protein Li 2a; F-box and WD repeats protein beta-TrCP; pIkappaBalpha-E3 receptor subunitHomo sapiens (human)
Nucleolar complex protein 2 homologProtein NOC2 homolog; NOC2-like protein; Novel INHAT repressorHomo sapiens (human)
Glutathione peroxidase 2GPx-2; GSHPx-2; EC 1.11.1.9; Gastrointestinal glutathione peroxidase; Glutathione peroxidase-gastrointestinal; GPx-GI; GSHPx-GI; Glutathione peroxidase-related protein 2; GPRP-2Homo sapiens (human)

Compounds (0)

CompoundDescription